Automatic Estimation of MDS-UPDRS Gait Scores from Videos with Multi-Rater Disagreements
Objective: Early diagnosis of Parkinson's disease (PD) and tracking its signs are crucial for developing treatment plans. The MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) defines…Using Machine Learning to Predict the Best Outcomes with Electrical Muscle Stimulation for Tremors in Parkinson’s Disease
Objective: This study explores the effect of electrical muscle stimulation (EMS) on resting tremor and aims to identify the best machine learning model to predict…MR guided high-intensity ultrasound thalamotomy in essential tremor and Parkinson´s disease: is there an ideal candidate?
Objective: To report the efficacy and safety of unilateral thalamotomy at Ventralis intermediate nucleus (VIM) by MR guided High-Intensity Focused Ultrasound (MRgHIFU) in treatment of…Synchronous or asynchronous exercises is beneficial compared to no exercise in Brazilian people with Parkinson’s disease during COVID-19 pandemic.
Objective: To compare the self-reported motor and non-motor symptoms in Brazilian people with Parkinson´s disease (PD) that performed home-based remotely exercise (asynchronous or synchronous) or…Optimizing an Electronic Health Records (EHR)-based Algorithm for Parkinson’s Disease Case Ascertainment
Objective: To develop an EHR-based algorithm to classify patients with PD into three levels of diagnostic certainty. Background: EHRs can be a rich source of…Model Innovation in Parkinson’s disease drug development: linking Quantitative Systems Pharmacology to the patient voice
Objective: There is a growing sense of urgency to integrate the voice of the patient in drug development in Parkinson’s disease (PD). Public private partnerships…Direct Costs of patients with Parkinson’s Disease in a region of the Brazilian Amazon
Objective: To evaluate the perception of the annual direct costs (medications, medical appointments, rehabilitation, transportation) associated with the treatment for patients with PD in the…Trunk postural control in seated position on a prototype of unstable chair and the interference of cognitive and motor tasks in individuals with Parkinson disease
Objective: To analyze trunk balance control of individuals with Parkinson disease (PD) in seated position and compare the control position with motor and cognitive tasks.…The EPSILON (Early ParkinSon wIth L-dopa/DDCi and OpicapoNe) study in early Parkinson’s disease: design and rationale of a phase III, double-blind, randomized, placebo-controlled study
Objective: This study aims to explore the potential of opicapone (OPC) to enhance the clinical benefit of levodopa (L-dopa)/dopa decarboxylase inhibitor (DDCi) in patients with…CVT-301 (levodopa inhalation powder): meta-analysis of safety in patients with Parkinson’s disease (PD)
Objective: Safety results from a phase 3, double-blind study of CVT-301 in patients with PD were combined with results from a 4-week, phase 2b, double-blind,…
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