Occupational Pesticide Exposure, Personal Protective Equipment, and Parkinson’s Disease: An Observational Study from the PPMI Cohort
Objective: To evaluate the association between occupational exposure to specific pesticides and Parkinson’s disease in participants from the PPMI Online cohort, and to determine whether…Beyond Motor Symptoms: Utilizing the FreeSurfer Brainstem Substructures Module to Characterize a Complex Parkinsonian Phenotype with Profound Dysautonomia
Objective: To describe the autonomic function profile and quantitative brainstem substructures analysis in a 62-year-old male of Parkinsonism complicated by severe autonomic failure and neuropsychiatric…Genome-wide Discovery of GBA1 Modifiers in Parkinsons Disease Carriers across Populations from the Global Parkinsons Genetics Program
Objective: To identify genetic risk modifiers for GBA1 risk variant carriers of European and African ancestry, we used data from GP2 (http://gp2.org/), the UK Biobank,…Bridging Genetics and Precision Medicine in Parkinson’s Disease through GP2: Translating Genetic Risk into Trial-Eligible GBA1 and LRRK2 Cohorts
Objective: To advance precision medicine in Parkinson’s disease (PD) by integrating large-scale clinico-genetic data from diverse populations worldwide and establishing a framework to characterize individuals…Towards Deep Learning for Personalized Parkinson’s Disease Tremor Segmentation and Severity Classification Using Wearable Sensors
Objective: The objective of this work is to develop and evaluate a deep learning framework for segmenting and classifying Parkinson’s disease (PD) resting tremor severity…Comparison of Non-Motor Outcomes after Subthalamic Nucleus versus Globus Pallidus Internus Deep Brain Stimulation in Parkinson’s disease
Objective: To compare non-motor symptom outcomes after globus pallidus internus (GPi) versus subthalamic nucleus (STN) deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: Non-motor…Discontinuation Patterns and Predictive Factors in Continuous Subcutaneous Foslevodopa/Foscarbidopa (FLC/FCD) Therapy: Insights from Early Clinical Experience
Objective: To characterize discontinuation patterns, reasons, and baseline predictors of therapy cessation in a prospective FLC/FCD cohort. Background: Real-world discontinuation rates for continuous subcutaneous FLD/FCD…Prevalence and Socio-Demographic Profile of Parkinson’s Disease in Rural Tanzania
Objective: To determine the prevalence and socio-demographic profile of Parkinson’s disease (PD) in a rural Tanzania and establish the disease burden to guide health policy.…Linking Motor and Non-Motor Fluctuations in Parkinson’s Disease
Objective: The aim of this study is to find a correlation between motor and non-motor symptoms fluctuation in parkinson’s disease. Background: Despite increasing awareness of…Interleukin 6 in the assessment of Parkinson’s disease and Progressive Supranuclear Palsy
Objective: The aim of this research is to analyze the relevance of serum interleukin 6 levels in the evaluation of Parkinson’s disease (PD) and Progressive…
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