Detrusor overactivity is associated with frontal dysfunction in patients with Parkinson’s disease?
Objective: To present the prefrontal cortex activity in patients with Parkinson's disease (PD) and evaluated the association between prefrontal cortex and lower urinary tract dysfunction…Impairment of decision-making processes in patients with Parkinson’s disease during a strategic game
Objective: To characterize differences in choice patterns, and differentiate the effects of dopaminergic (DA) treatment on motor and cognitive function, during dynamic decision-making in Parkinson's…Temporal working memory deficit in Parkinson’s disease
Objective: To investigate whether temporal working memory (TWM) could be impacted in Parkinson's disease (PD). We also tested whether idiopathic PD patients (iPD) could be…Catechol-o-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson’s disease
Objective: The Catechol-O-Methyltransferase (COMT) Val158Met polymorphism has been proposed to be associated with increased risk of PD and have a specific impact on dopamine-mediated prefrontal…Optogenetic silencing of locus coeruleus activity in mice impairs cognitive flexibility in an attentional set-shifting task
Objective: In this study we used unilateral optogenetic silencing of the LC in an attentional set-shifting task (ASST) to evaluate the influence of the LC…