Phenotypic Evolution from Nonfluent PPA to PSP
Objective: Progressive Supranuclear Palsy (PSP) and Nonfluent Primary Progressive Aphasia (nfvPPA) are clinicopathological entities within the 4-repeat tauopathy (4R tauopathy) spectrum. Increasing evidence suggests that…Logopenic Aphasia After Thalamotomy in Parkinson’s Disease: A Case Report
Objective: To describe a case of acute-onset, progressive language impairment resembling PPA developing after RF thalamotomy in a patient with PD. Background: Primary progressive aphasia…Early Overlap of Corticobasal Syndrome and Richardson Syndrome in Corticobasal Degeneration: Evidence from 252 Autopsy-Confirmed Cases
Objective: This study aimed to identify early clinical phenotypes of corticobasal degeneration (CBD) using unsupervised analysis of a large clinicopathologic dataset. Background: Early diagnosis of…Laryngeal Dystonia, Dopa-Responsive Parkinsonism and Primary Progressive Aphasia with Alzheimer Disease Pathology
Objective: To report a case of laryngeal dystonia (LD), parkinsonism and primary progressive aphasia (PPA) with Alzheimer disease (AD) pathology Background: The presence of 3-4 neurological…Stepping backwards to move forward A case study on novel PT interventions for DLB
Objective: Explore the effectiveness of backwards walking and backwards stepping interventions to improve gait stability and balance in persons with Dementia with Lewy Bodies (DLB).…Language impairment in Corticobasal Syndrome: from clinical phenotype to biomarkers
Objective: To investigate the language impairment profile of patients diagnosed as probable Corticobasal Syndrome (CBS) [1] in light of a multimodal imaging biomarkers analysis, namely…Movement disorders spectrum in patients with frontotemporal dementia
Objective: To determine frequency of different hypokinetic and hyperkinetic movement disorders (MD) within a spectrum of frontotemporal dementia (FTD): we examined patients with behavioral and…Dorsal simultanagnosia as a cortical sign in the tauopathy spectrum
Objective: Clinical characterization of a tauopathy spectrum patient. Background: In recent years phenotypic overlap has been demonstrated between patients with progressive supranuclear palsy (PSP) pathology…Primary progressive aphasia and frontotemporal dementia in an Irish-American family due to a novel progranulin mutation
Objective: To report the first Irish family with FTLD and a novel granulin (GRN) mutation. Background: Frontotemporal lobar degeneration (FTLD) is the second most common…
