Video-oculography for enhancing the diagnostic accuracy of early oculomotor dysfunction in Progressive Supranuclear Palsy
Objective: To test (1) the role of video oculography (VOG) in the detection of slow saccades in two common subtypes of Progressive Supranuclear Palsy (PSP)…Early Syndromes and Clinicopathologic Progression in Progressive Supranuclear Palsy
Objective: We aimed to characterize early clinical features of progressive supranuclear palsy (PSP) that might correlate with clinical course and neuropathologic findings. Background: Progressive supranuclear…Frontal atrophy in progressive supranuclear palsy[PSP] -an universal feature along with midbrain atrophy?
Objective: To see if frontal atrophy is a frequent radiologic feature of PSP on MRI imaging . Background: Progressive supranuclear palsy[PSP] is a taupathy that…Combined application of alpha-synuclein and 4-repeat tau seed amplification assays for the differential diagnosis of parkinsonian disorders
Objective: To assess alpha-synuclein (a-syn) and 4-repeat tau (4RT) seed amplification assay (SAA) positivity rates in biosamples from people with Parkinson’s disease (PD) and Progressive…Progressive freezing of gait in atypical parkinsonism. A Possible Progressive Supranuclear Palsy phenotype.
Objective: Report a case of progressive freezing of gait diagnosed as a Possible Progressive Supranuclear Palsy phenotype Progressive Gait Freezing. Background: PSP is the most…[18F]PR04.MZ PET CT as a clinical tool in the differential diagnosis of PD and other atypical parkinsonian syndromes in the first 5 years of symptoms
Objective: Investigate if the [18F]PR04.MZ PET CT is a useful tool in the differential diagnosis of PD and atypical parkinsonian syndromes (AP), mainly MSA and…Identification of underlying Lewy body pathology in primary tauopathies by α-synuclein seed amplification assay
Objective: To determine intravitam prevalence of α-synuclein (αSyn) pathology in primary tauopathies, such as PSP and CBS, by αSyn seed amplification assay (synSAA) Background: Neuropathological…PSP: a Clinical Case
Objective: PSP is traditionally considered a neurodegenerative disease of late life. Its diagnostic criteria include the item “age of onset over 40 years.” This significantly…Hierarchical Machine Learning Classification of Parkinsonian Disorders using Saccades
Objective: To evaluate the discriminative power of a novel saccade waveform reconstruction approach compared to conventional saccadic metrics in differentiating Parkinson's disease (PD), progressive supranuclear…Dermal 4R-Tau seeding as a novel biomarker for Progressive Supranuclear Palsy
Objective: To ascertain the presence of misfolded tau species in the skin of Progressive Supranuclear Palsy (PSP) patients and evaluate its utility as a potential…
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