MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Resting brain metabolism"

  • 2023 International Congress

    Metabolic connectivity assessed by dynamic FDG-fPET acquisition in Parkinson’s disease: a multimodal fPET and fMRI study

    M. Ruppert-Junck, V. Heinecke, K. Steidel, M. Beckersjürgen, D. Librizzi, M. Luster, H. Müller, F. Verburg, L. Timmermann, C. Eggers, D. Pedrosa (Marburg, Germany)

    Objective: To examine the spatial convergence of hemodynamic and metabolic network characteristics based on dynamic [18F]FDG-fPET acquisition Background: While fMRI reveals within-subject hemodynamics, [18F]FDG-PET traditionally…
  • 2023 International Congress

    Patterns of Parkinson disease mitochondrial brain function indexed by 31P magnetic resonance spectroscopy

    F. Lopez, C. Hess, A. Ray, R. O'Connell, A. O'Shea, L. Kenney, A. Ratajska, G. Alexander, A. Woods, M. Okun, D. Bowers (Gainesville, USA)

    Objective: To examine whether individuals with PD show greater temporal than frontal high energy phosphate metabolism (31P MRS ATP) that is similar or different from…
  • 2023 International Congress

    Functional network correlates of APOE ε4 allele in Parkinson’s disease

    K. Schindlbeck, A. Vo, P. Mattis, N. Nguyen, D. Eidelberg (Munich, Germany)

    Objective: To investigate the influence of APOE ε4 allele on metabolic network activity and functional connectivity in patients with Parkinson's disease (PD). Background: Disease progression…
  • 2023 International Congress

    Network analysis of brain perfusion in [11C]UCB-J PET: Parkinson’s related motor pattern (PDRP)

    P. Honhar, S. Tinaz, S. Holmes, M. Dias, M. Naganawa, J. Gallezot, S. Henry, R. Comley, N. Nabulsi, Y. Huang, A. Hillmer, R. Carson, S. Finnema, D. Matuskey (New Haven, USA)

    Objective: The aim was to investigate the use of R1 (relative delivery parameter) as a surrogate of blood perfusion to identify brain networks specific to…
  • 2023 International Congress

    The hypometabolism in anterior cingulate gyrus and thalamus: potential biomarkers of disease progression in progressive supranuclear palsy

    B. Wang, H. Wang (Hangzhou, China)

    Objective: This study aimed to identify differences in FDG uptake and metabolic covariant network (independent component analysis) in progressive supranuclear palsy (PSP) in comparison with…
  • 2023 International Congress

    Machine learning diagnosis of parkinsonian syndromes: network approach with two different sites

    M. Perovnik, T. Rus, A. Vo, N. Nguyen, P. Tomše, J. Jamšek, C. Tang, M. Trošt, D. Eidelberg (Ljubljana, Slovenia)

    Objective: To test an automated differential diagnostic algorithm for parkinsonian syndromes based on machine learning and FDG-PET scans using subject scores for sets of validated…
  • 2022 International Congress

    Whole-brain metabolic pattern analysis of faciobrachial dystonic seizures (FBDS)

    J. Mo, K. Zhang, X. Shao (Beijing, China)

    Objective: Whole-brain metabolic network analysis was performed to 1) identify the symptomatic network of faciobrachial dystonic seizures (FBDS); 2) to explore independent neuroimaging predictors; and…
  • 2022 International Congress

    Analyzing the metabolic function of DJ-1 in the pathogenesis of Parkinson`s disease (PD) and Glioblastoma multiforme (GBM)

    P. Mencke (Esch-sur-Alzette, Luxembourg)

    Objective: In this project, we are comprehensively studying the function of DJ-1 in PD and GBM to better understand its observed role in both, neurodegeneration…
  • 2022 International Congress

    BRAIN REGIONAL HYPOMETABOLISM PROGRESSION IN iRBD: THE COGNITIVE ROLE OF OCCIPITAL HYPOMETABOLISM

    G. Carli, S. Meles, A. Janzen, D. Perani, W. Oertel, K. Leenders (Groningen, Netherlands)

    Objective: To understand functional brain changes over time in isolated REM sleep behaviour disorder (iRBD), we investigated the progression of regional hypometabolism in iRBD patients…
  • 2022 International Congress

    Reconfiguration of Functional Motor Connectome after MRgFUS Vim Thalamotomy in Essential Tremors

    M. Stanziano, S. Palermo, JP. Medina, G. Demichelis, D. Fedeli, G. Messina, N. Golfrè Andreasi, S. Rinaldo, A. Redolfi, G. Devigili, V. Levi, F. Ghielmetti, G. Frazzetta, L. D'Incerti, M. Grisoli, F. Di Meco, A. Nigri, MG. Bruzzone, R. Eleopra (Milan, Italy)

    Objective: Our primary endpoint was to verify whether rs-FC between tremor-related areas was effectively modulated by MRgFUS at 1 and 3 months post-operatively.  Alongside, we…
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