Segregation of subjective and objective clinical measures in Parkinson’s disease
Objective: Use standardized measures to characterize disease severity, progression, and outcomes in Parkinson’s disease (PD). Background: Subjective and objective standardized measures are usually performed in…Development of a Paroxysmal Movement Disorder Diary for Patients with Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)
Objective: To perform qualitative research to develop and establish content validity of a new clinical outcome assessment (COA) instrument for paroxysmal movement disorders in Glut1…Item Response Theory Analysis of the MDS-UPDRS Items
Objective: To investigate the measurement characteristics of the MDS-UPDRS using item response theory (IRT) approaches. Background: The MDS-UPDRS has become the most frequently used assessment…Assessments of Movement Disorder Symptoms and Functional Impacts in Glucose Transporter Type 1 Deficiency Syndrome (Glut1 DS)
Objective: To identify Clinical Outcome Assessments (COAs) appropriate for the evaluation of paroxysmal movement disorder symptoms and functional impact in Glut1 DS. Background: Glut1 DS…Differential Item Functioning in the Unified Dyskinesia Rating Scale (UDysRS)
Objective: Test if differential item functioning (DIF) due to gender, age, race/ethnicity or education level is present in UDysRS items. Background: Testing a rating…Using measurements from wearable sensors for automatic scoring of Parkinson’s disease motor states
Objective: The aim of this study was to investigate the concurrent validity of an objective gait measure for assessment of motor states in advanced Parkinson’s…The 3-step clinical prediction tool for falls in Parkinson’s disease: can it be used as a self-assessment measure?
Objective: To determine if people with Parkinson’s disease (PD) are able to estimate their gait speed relative to a threshold speed of 1.1 m/s. Background:…PDSS: A Novel Mobile-based Parkinson Disease Severity Score
Objective: To propose a novel mobile-based Parkinson Disease Severity Score (PDSS) to provide high resolution and objective severity monitoring for patients in the home setting.…Physical Activity in Early Parkinson Disease
Objective: To characterize physical activity habits in patients with early Parkinson disease (PD). Background: Physical activity is an important therapy for PD as it may…Autonomous Tracking of Body Bradykinesia during Unconstrained Activities in Parkinson’s Disease
Objective: To develop an algorithm for real-time automated detection of body bradykinesia during unconstrained activities using combined inertial measurement (IMU) and electromyographic (EMG) sensor data.…
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