Incidence of drooling in Parkinson’s Disease and Impact on Quality of Life
Objective: The project aimed to determine the frequency and severity of drooling in the Parkinson’s Disease (PD) population in Cardiff & the Vale Health-board through…Glycopyrrolate as inhalation for treating sialorrhea in Parkinson’s Disease
Objective: To evaluate the safety, tolerability and effect of glycopyrrolate inhalations in PD patients with sialorrhea. Background: Sialorrhea is reported in up to 60 percent…Effects of Botulinum Toxin treatment for sialorrhea in patients with cerebral palsy
Objective: To evaluate the benefits of treatment of drooling with Botulinum Toxin Type A (AbobotulinumtoxinA) in patients with cerebral palsy. Background: Patients with cerebral palsy…Efficacy of incobotulinumtoxinA in patients with sialorrhea, as assessed using the modified Radboud Oral Motor Inventory for Parkinson’s disease (mROMP): Results of the SIAXI study
Objective: The pivotal double-blind, randomised Phase III SIAXI study (NCT02091739), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U for sialorrhea. Co-primary endpoints…Long-term efficacy and safety of incobotulinumtoxinA treatment for sialorrhea in Parkinson’s disease and other neurologic conditions
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with a 48-week extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 U or…Impact of injection guidance techniques on the efficacy and safety of incobotulinumtoxinA for sialorrhea
Objective: SIAXI (NCT02091739), a pivotal double-blind, randomised, placebo-controlled study with an extension period (EP), assessed the efficacy and safety of incobotulinumtoxinA 75 or 100 U…The impact of divided attention in dual task conditions on drooling in Parkinson’s Disease (PD): a pilot study
Objective: To investigate whether frequency of saliva swallows reduced, and drooling severity and frequency increased, when people with PD engaged in a distracting cognitively demanding…Saliva changes and the oral health in Parkinson´s disease
Objective: The aim of this study was to determine the risk of change in the oral microflora and oral health in PD patients. Background: Parkinson…A comprehensive characterisation of the salivary proteome of patients with Parkinson’s disease
Objective: To comprehensively characterise the salivary proteome of patients with Parkinson's disease (PD) and generate potential biomarker candidates for future studies. Background: Saliva may be…Awareness and perception of gastrointestinal symptoms in Parkinson´s disease: A survey of patients and caregiving relatives
Objective: The purpose of this survey was to determine the awareness and perception of gastrointestinal (GI) symptoms in patients and caregiving relatives (for simplicity hereunder…