Automated VMAT2 [18F]AV-133 PET analysis in Parkinson’s disease
Objective: To evaluate a fully automated image analysis pipeline to process vesicular monoamine transporters type 2 (VMAT2) [18F]AV-133 tracer positron emission tomography (PET) images, by…Blood NfL can track progression in multiple system atrophy
Objective: To validate the role of NfL for disease progression, severity and subject trial selection in MSA. Neurofilament light (NfL) was explored in this regard though…Network attack tolerance: A resilience proxy for Parkinson’s disease?
Objective: To investigate if individual capacity in network attack tolerance moderates the relationship between striatal dopamine loss and symptom severity in PD. Background: It was…Gold and silver nanoparticle-based Localized Surface Plasmon Resonance Sensor (LSPR) for the detection of histidine as a potential biomarker in Parkinson’s Disease.
Objective: Previous literature has proven that histamine has a crucial role in the process of neuroinflammation in Parkinson's Disease (PD) . We can indirectly detect…TRPV4 Mutation related Parkinson’s Disease with Scapuloperoneal spinal muscular atrophy
Objective: Scapuloperoneal spinal muscular atrophy (SPSMA) is a rare autosomal dominant disease caused by transient receptor potential cation channel (TRPV4) gene, involving scapular and peroneal…Height and nigral neuron density in Parkinson’s disease
Objective: To investigate the possible relationship between height and the density of neurons in the substantia nigra pars compacta (SNc). Background: The dopaminergic system modulates…Striatal dopamine transporter imaging in Parkinson’s disease drug-naïve patients: focus on sexual dysfunction
Objective: To evaluate whether the 123I-FP-CIT striatal uptake differs in Parkinson’s disease (PD) drug-naïve patients with and without sexual dysfunction. Background: Sexual dysfunction is one…Disease progression characterized by motor performance, dopaminergic neurodegeneration and T cell infiltration in the transgenic hm2-α-SYN-39 mouse model of Parkinson´s disease
Objective: To study disease progression in the transgenic (tg) hm2-α-SYN-39 mouse model of Parkinson´s disease (PD) by assessment of motor performance, dopaminergic neurodegeneration and T…To compare early / late onset MSA from the PAN American MSA (PANMSA) database
Objective: Compare two different cohorts of patients with the same pathology differentiated by age of onset. Background: Multiple system atrophy (MSA) is a rare neurodegenerative…Probabilistic tractography study of the nigrostriatal pathway in Parkinson’s disease
Objective: To investigate changes in connectivity of the nigrostriatal and striatonigral pathways in PD and association with clinical symptoms. Background: Loss of dopaminergic neurons in…