Kratom withdrawal induced orobuccal dyskinesia
Objective: To describe the new observation of Kratom withdrawal that presented with the choreiform movement of lips and tongue. Background: Orobuccal dyskinesia is the hyperkinetic…Deutetrabenazine Treatment Response by Concomitant Dopamine-Receptor Antagonists in the Phase III, Randomized, Double-Blind, Placebo-Controlled AIM-TD Trial in Tardive Dyskinesia
Objective: To determine the impact of dopamine-receptor antagonist (DRA) use at baseline on the efficacy, safety, and tolerability of deutetrabenazine in patients with tardive dyskinesia…An MCID for AIMS Dyskinesia Total Score Change in Subjects with Tardive Dyskinesia
Objective: To establish a minimal clinically important difference (MCID) for Abnormal Involuntary Movement Scale (AIMS) dyskinesia total score change using data from randomized, double-blind, placebo…Deutetrabenazine is Associated with an Improvement in Involuntary Movements in Patients With Tardive Dyskinesia as Seen by the High Proportion of Responders to Deutetrabenazine Treatment in the AIM-TD Study
Objective: To examine response rates between patients receiving deutetrabenazine and placebo. Response levels were pre-specified from 10–90% improvement from baseline in Abnormal Involuntary Movement Scale…Evaluation of Patient-Reported Outcomes in Tardive Dyskinesia Patients With Underlying Psychotic and Mood Disorders in the ARM-TD and AIM-TD Trials
Objective: To assess patients’ impression of treatment benefit from deutetrabenazine (DTB) for the treatment of tardive dyskinesia (TD). Background: In TD, patients’ perception of benefit…Estimation of Tardive Dyskinesia Incidence and Prevalence in the United States
Objective: To estimate the current and expected epidemiology of tardive dyskinesia (TD) in the United States (US), stratified by level of severity. Background: TD is…Addressing Involuntary Movements in Tardive Dyskinesia (AIM-TD): Improvements in Clinical Global Impression of Change (CGIC) with Deutetrabenazine Treatment in Tardive Dyskinesia (TD)
Objective: To determine the efficacy of deutetrabenazine in patients with TD as measured by CGIC. Background: TD is often irreversible and can affect any body…Effect of Deutetrabenazine by Body Region Score of the Abnormal Involuntary Movement Scale in Tardive Dyskinesia: ARM-TD and AIM-TD Studies
Objective: To assess the efficacy and safety of deutetrabenazine (DTB) in reducing the severity of the abnormal involuntary movements of tardive dyskinesia (TD) based on…Addressing Involuntary Movements in Tardive Dyskinesia (AIM-TD): Efficacy, Safety, and Tolerability of Fixed-Dose Deutetrabenazine for the Treatment of Tardive Dyskinesia
Objective: To evaluate the efficacy, safety, and tolerability of deutetrabenazine in patients with tardive dyskinesia (TD). Background: AIM-TD is the second large 12-week, Phase III,…Healthcare Utilization and Costs for Patients With Tardive Dyskinesia
Objective: To assess healthcare utilization and costs pre- and post-tardive dyskinesia (TD) diagnosis in a sample of patients from the commercially insured and Medicare Supplemental…
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