MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • MDS Virtual Congress 2020

    Among Parkinson’s disease patients with both OFF and dyskinesia, ADS-5102 (amantadine) extended-release reduces disruptive motor episodes and improves function: Analysis of phase 3 trials

    R.A Hauser, D. Chernick, A. Formella (Tampa, FL, USA)

    Objective: Evaluate the effects of ADS-5102 (amantadine) extended release capsules on motor complications and functional outcomes among patients experiencing both troublesome dyskinesia and OFF (disruptive…
  • MDS Virtual Congress 2020

    Use in Clinical Practice of a Personalised and Long-term Monitoring Device for Parkinson´s Disease: STAT-ON

    D. Santos García, N. López Ariztegui, E. Cubo, A. Vinagre Aragón, R. García Ramos, C. Borrué, G. Fernández Pajarín, N. Caballol, I. Cabo, J. Barrios López, J. Hernández Vara, M.A Avila, C. Gasca Salas, S. Escalante, P. Manrique, R. Pérez Noguera, M. Álvarez Sauco, M. Sierra, M.G Monje, A. Sánchez Ferro, S. Novo, F. Alonso, D. Macías, I. Legarda, A. Rojo, I. Fernández, M.T Buongiorno, P. Pastor, P. García Ruíz (A Coruña, Spain)

    Objective: To analyze the opinion of different neurologists from Spain about the STAT-ON tool after using the device in a real clinical practice setting (RCPS).…
  • MDS Virtual Congress 2020

    Reduction of OFF time with apomorphine infusion during hours of pump use: Analysis from a Phase III, open-label study

    S. Isaacson, A. Espay, R. Pahwa, T. Clinch, P. LeWitt (Boca Raton, FL, USA)

    Objective: Evaluate the efficacy of apomorphine (APO) infusion in reducing OFF time during the hours of pump use in PD patients with motor fluctuations inadequately…
  • 2019 International Congress

    Laboratory Performance of the DopaFuse® Delivery System

    R. Draper, J. Harmon, A. Heller, B. Heller, E. Heller, C. King, T. Lau, P. Plante, J. Spiridigliozzi (Austin, TX, USA)

    Objective: SynAgile has developed the DopaFuse Delivery System to noninvasively and continuously administer levodopa/carbidopa (LD/CD) into the mouths of patients with Parkinson’s Disease (PD). The…
  • 2019 International Congress

    STAT-ON: a Wearable Inertial System to Objectively Evaluate Motor Symptoms in Parkinson’s Disease

    D. Rodriguez-Martin, C. Pérez-López, A. Samà, M. Pié, A. Català, J. Cabestany, A. Rodríguez-Molinero (Vilanova I Geltrú, Spain)

    Objective: We present a wearable inertial system for the evaluation of motor symptoms in Parkinson's Disease. Background: PD is the second neurodegenerative disease affecting to around…
  • 2019 International Congress

    A Thorough QT Study of Apomorphine Sublingual Film in Patients With Parkinson’s Disease Complicated By “OFF” Episodes

    F. Stocchi, K. Wilks, E. Peckham, M. de Pandis, K. Sciarappa, F. Agbo, R. Kleiman, D. Blum, B. Navia (Rome, Italy)

    Objective: To assess the effect of apomorphine sublingual film (APL130277; APL) on the QT interval in patients with Parkinson’s disease (PD) and “OFF” episodes participating…
  • 2019 International Congress

    Effect of an Increase in Dose of Istradefylline, an A2A Receptor Antagonist, in Levodopa (LD)-Treated Patients with Parkinson’s Disease (PD)

    N. Hattori, T. Nomura, P. Salzman, H. Kitabayashi, M. Ishiuchi, K. Toyama, A. Mori (Tokyo, Japan)

    Objective: To observe whether increasing the istradefylline dose from 20 to 40mg/day provides more patients with meaningful clinical responses. Background: Istradefylline, a well-tolerated selective adenosine…
  • 2019 International Congress

    Does information from the Personal KinetiGraph™ (PKG) influence neurologists´ treatment decisions?

    M. Sundgren, P. Rousu, A. Johansson (Stockholm, Sweden)

    Objective: To evaluate if PKG data influences neurologists´ treatment decisions in routine clinical care of patients with Parkinson´s disease. Background: The PKG movement recording system is…
  • 2019 International Congress

    A characterization of the ADL-level in daily life with Parkinson`s Disease based on objective measurements and subjective experiences.

    T. Thomsen, T. Kjær, L. Jørgensen, A. Haahr, K. Winge (Roskilde, Denmark)

    Objective: 1. Test whether slow response to the medication and EMO-periods (Early Morning Off), affects the patient`s experience of being able to perform ADL-functions. 2.…
  • 2019 International Congress

    Efficacy of Istradefylline, an A2A Receptor Antagonist, When Added to Levodopa (LD) and Other Medications for Parkinson’s Disease (PD)

    P. Lewitt, N. Hattori, A. Mori, K. Toyama, E. Ohta, P. Salzman, S. Isaacson (West Bloomfield, MI, USA)

    Objective: To evaluate the clinical effect of istradefylline as adjunctive treatment to LD in PD patients with or without additional PD medications (meds). Background: Istradefylline,…
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