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Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Wearing-off fluctuations"

  • 2026 International Congress

    Ecological Momentary Assessment Monitoring Captures Motor Fluctuation Improvement after DBS in Parkinson’s Disease

    L. Drescher, J. Schikora, L. Feldmann, V. Witzig, P. Nonella, G. Brandt, GH. Schneider, J. Habets, A. Kühn (Berlin, Germany)

    Objective: To evaluate whether mobility measures based on ecological momentary assessment (EMAs) capture deep brain stimulation (DBS) motor improvement in Parkinson’s disease (PD) and correlate with clinician-rated motor impairment (UPDRS III) and motor…
  • 2026 International Congress

    Sex-Specific Differences in Parkinson’s Disease: A Retrospective Analysis of over 10,000 Patients from the Paracelsus-Elena Hospital, a Specialized Movement Disorder Clinic in Germany

    S. Weber, S. Schnell, H. Aust, C. Trenkwalder, B. Mollenhauer (Goettingen, Germany)

    Objective: To analyze sex differences in PD in a large cohort from a hospital specializing in PD and other movement disorders. Background: Sex differences in…
  • 2026 International Congress

    Exposure-Response Analysis of Glovadalen in the ATLANTIS Phase II Study: Trial Simulation Explains Dose-Response for OFF Time in Parkinson’s

    D. Menshykau, M. Biagioni, C. Beuter, C. Legendre, A. Benoit, L. Vroye, B. Klünder, M. Faisal, S. Leach, R. Nicholl, H. Naik (Monheim am Rhein, Germany)

    Objective: This analysis characterized the exposure-response (E-R) relationship of glovadalen (UCB0022) in the ATLANTIS Phase-IIa proof-of-concept study, to understand the apparent lack of dose-response for…
  • 2026 International Congress

    Impact of Multi-day Wearable Monitoring on Neurologists’ Assessment of Motor Fluctuations and Treatment Strategies in Parkinson’s Disease: A Real-World Study

    M. Borrell-Pichot, L. Pérez-Carasol, A. Campolongo, B. Pascual-Sedano, R. Martínez-Fernández, JA. Aibar-Rodríguez, J. Kulisevsky, I. Aracli-Bolaños (Barcelona, Spain)

    Objective: To assess the impact of wearable-device objective metrics on neurologists’ perception and therapeutic decisions in a real-world cohort of patients with Parkinson’s disease (PD).…
  • 2026 International Congress

    Markerless Kinematics of Levodopa Response During Activities of Daily Living in Parkinson’s Disease

    J. Yun, S. Haar (London, United Kingdom)

    Objective: To determine whether markerless motion tracking during activities of daily living (ADLs) can identify kinematic changes during medication wearing-off as Parkinson's disease (PD) patients…
  • 2026 International Congress

    Motor Fluctuations and Dyskinesias in LRRK2-Associated Parkinson’s Disease

    A. Agrebaoui, R. Zouari, A. Mousli, F. Nabli, D. Ben Mohamed, A. Rachdi, MZ. Saied, S. Ben Sassi (Tunis, Tunisia)

    Objective: To characterize motor fluctuations and dyskinesias in patients with LRRK2-associated Parkinson’s disease. Background: Motor complications, including dyskinesias and motor fluctuations, are hallmarks of advanced…
  • 2026 International Congress

    Comparison Of Levodopa Dose Frequency And Parkinson’s Kinetigraph Metrics For Screening Advanced Parkinson’s Disease

    N. Ullah, H. Renduchintala, B. Mohamed, J. Adenwalla (Cardiff, United Kingdom)

    Objective: 1. Evaluate how well levodopa dose frequency and Parkinson's Kinetigraph (PKG) metrics correspond with the 5-2-1 criteria for identifying Advanced Parkinson Disease (APD)2. Determine…
  • 2026 International Congress

    Risk factors for dysautonomic fluctuations in Mexican PwP

    MF. Medina-Pérez, MF. Velasco-Delgado, A. Cervantes-Arriaga, R. Solís-Vivanco, M. Rodríguez-Violante (Mexico City, Mexico)

    Objective: To identify risk factors for non-motor dysautonomic fluctuations in people living with Parkinson’s disease (PwP). Background: Advanced Parkinson’s disease (PD) is characterized by motor…
  • 2026 International Congress

    Are we overlooking wearing off? Evaluating the role of the WOQ-9 questionnaire in routine Parkinson’s care

    G. Heery, B. Mohamed, J. Adenwalla (Cardiff, United Kingdom)

    Objective: 1. Evaluate clinicians’ ability to recognise wearing-off compared with the Wearing Off Questionnaire-9 (WOQ-9)2. Assess patient awareness of wearing-off symptoms Background: Wearing off is…
  • 2026 International Congress

    Comparative efficacy and safety of Safinamide versus Opicapone in Japanese patients with Parkinson’s Disease and wearing-off: A matching-adjusted indirect comparison

    N. Nishikawa, R. Ando, T. Ishida, T. Hatano, N. Hattori, M. Nomoto (Tokyo, Japan)

    Objective: To compare efficacy and safety outcomes with safinamide and opicapone as adjuncts to levodopa in Parkinson’s disease (PD) patients with wearing-off using an anchored…
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