Objective: We aimed to study an occurrence of Parkinson’s syndrome (PS), its relationship with duration of disease and age of patients with rheumatoid arthritis.

Background:

Rheumatoid arthritis (RA) is a severe systemic disease which leads besides of points and organs to the defeat of central nervous system.

Methods: The Clinical research was carried out in the department of rheumatology of the first clinic of Tashkent Medical Academy. We did neurologic exam in 80 patients with RA and did MRI angiography patients with PS. They aged 18-65 years (mean age 47 ± 1,6 years), of them 36  women and 14 men, 71.1% and 28.9% respectively. We eliminated patients with inherited Parkinson’s disease.

Results:

Patients aged 40-60 years were the most common of all patients we studied. The duration of the disease lasts from 1.5 months to 27 years. The average duration of the disease is 10.5 years. In neurologic exam we found muscular rigidity in hands, amimia of face, absence of synkinetic reactions and finger tremor. We detected in 19 (23,75%) patients rigidity form and in 5 (6,25%) patients tremor form of PS. In MRI scan of all patients with PS we found the many rheumatoid vasculitis of subcortical nucleus vessels.

Conclusions: We concluded that PS is occurs in patients with RA to 20-25% more often, than its occurrence in all population. Rigidity form of PS   amounts 79%. The severity of PS is higher than the RA is longer and the age of the patients greater.

References: https://precis2.preciscentral.com/Page.aspx?NID=A9B51E47CFDF4783&P=D805325BAA88D2EA47EC71FA167CF80D&Rnd=636166049549619787

« Back to 2017 International Congress

MDS Abstracts - https://www.mdsabstracts.org/abstract/randomize-study-of-occurrence-of-parkinsons-syndrome-in-patients-with-rheumatoid-arthritis/