Category: Parkinson's Disease: Pathophysiology
Objective: Comparison of serum IL-6 levels in Parkinson’s disease (PD) patients with and without Сovid-19.
Background: In the scientific literature, there is information about the increase in the amount of ferritin in the blood serum of patients after the infection of Sovid-19 and the prognosis of the complications of the disease.
Method: A total of 90 patients with PD were examined. Patients with PD were divided into 2 groups. Group 1 consisted of 45 patients with PD and Covid-19 infection, and group 2 consisted of 45 patients with PD and no Сovid-19 infection. The control group was patients who underwent Covid-19 without PD. The amount of IL-6 was checked using the IFA method.
Results: Patients suffering from akinetic-rigid form of PD in group 1 had a serum ferritin level of 316.5±8.2 ng/ml, 301.1±9.3 ng/ml in quivering PD and 314.6±7 in mixed form. It was found to be 2 pg/ml. The result of the comparison is that there was no reliable difference between the tremor and the mixed form of the disease, r≥0.05. The serum ferritin content of patients with PD 1st stage in group 1 was 282.4±8.6, the serum ferritin content of 2nd stage patients was 301.9±6.1 ng/ml, and the 3rd stage was mixed 352.2±8.3 ng/ml ng/ml and in stage 4 it was found to be 392.2.±7.8 ng/ml. The result of the comparison is that a reliable difference was observed between all stages of the disease, r≤0.001.
Conclusion: The level of ferritinemia in patients with Covid-19 is closely related to the clinical forms and stages of the disease. Ferritinemia has higher indicators in the akinetic-rigid form of the disease compared to the shaky and mixed forms, and in the higher stages of the disease compared to the lower stages.
To cite this abstract in AMA style:
B. Amonov, R. Matmurodov, B. Muminov. Levels of ferritinemia in Parkinson’s disease patients who underwent Covid-19 [abstract]. Mov Disord. 2024; 39 (suppl 1). https://www.mdsabstracts.org/abstract/levels-of-ferritinemia-in-parkinsons-disease-patients-who-underwent-covid-19/. Accessed October 5, 2024.« Back to 2024 International Congress
MDS Abstracts - https://www.mdsabstracts.org/abstract/levels-of-ferritinemia-in-parkinsons-disease-patients-who-underwent-covid-19/