MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2019 International Congress

    Molecular Integration in Neurological Diagnosis (MIND): A Center-Wide Approach to Improve Molecular and Genetic Characterization of Parkinson’s Disease

    T. Tropea, J. Rick, N. Han, S. Rudovsky, A. Siderowf, V. van Deerlin, A. Chen-Plotkin (Philadelphia, PA, USA)

    Objective: To develop a clinical and genetic repository of all patients with Parkinson’s disease at The University of Pennsylvania Parkinson’s Disease and Movement Disorders Center…
  • 2019 International Congress

    Assessment of Neuropsychological Outcomes Using a New Multiple Source, Constant- Current Rechargeable Deep Brain Stimulation System for the Treatment of Parkinson’s Disease – INTREPID Study

    A. Tröster, R. Jain, L. Chen, I. Study Group, M. Okun (Phoenix, AZ, USA)

    Objective: To evaluate neuropsychological outcomes in subjects participating in the INTREPID randomized controlled trial (RCT). Background: Neuropsychological evaluation in the context of Deep Brain Stimulation…
  • 2019 International Congress

    Asymmetry of motor symptoms in patients with Parkinson’s Disease

    Y. Trufanov, N. Svyrydova, V. Svistun, I. Harkava, H. Bondarenko, N. Zhhilova (Kyiv, Ukraine)

    Objective: The objective of our research was to investigate the asymmetry of motor symptoms in patients with Parkinson’s Disease (PD). Background: In most PD cases…
  • 2019 International Congress

    The relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s Disease

    Y. Trufanov, N. Svyrydova, V. Svistun, I. Harkava, H. Bondarenko, N. Zhhilova (Kyiv, Ukraine)

    Objective: The objective of our research was to study the relationship between the motor onset and the asymmetry of motor symptoms in patients with Parkinson’s…
  • 2019 International Congress

    Identification of candidates for device-assisted therapy in Parkinson’s disease using Artificial Neural Networks

    C. Valderrama Martín, L. Triguero Cueva, MJ. Pérez Navarro, CJ. Madrid Navarro, R. Calle Calle, I. Rego García, A. Mínguez Castellanos, IM. Galván León, F. Escamilla Sevilla (Granada, Spain)

    Objective: To use Multilayer Perceptron (MLP), an artificial neural network, to identify candidates for device-assisted therapy (DAT) among patients with Parkinson's disease (PD) Background: DAT…
  • 2019 International Congress

    Two-year outcome of autologous peripheral nerve grafting to the substantia nigra at the time of DBS surgery in patients with Parkinson’s disease

    C. van Horne, J. Quintero, J. Slevin, J. Gurwell, Z. Guduru, A. Welleford, N. El Seblani, G. Gerhardt (Lexington, KY, USA)

    Objective: Assess 2-year safety, feasibility, and clinical outcomes of implanting a unilateral peripheral nerve graft to the substantia nigra in patients with Parkinson’s disease at…
  • 2019 International Congress

    Botulinum toxin type A therapy in a movement disorders unit: a 23-year experience.

    M. Velez, C. Cosentino, L. Torres (Lima, Peru)

    Objective: To update the experience with botulinum toxin type A therapy at the Unidad de Movimientos Involuntarios (UMI) of Instituto Nacional de Ciencias Neurologicas (INCN)-Lima,…
  • 2019 International Congress

    SAFINAMIDE IN DAILY CLINICAL PRACTICE: ASSESSMENT OF EFFICACY AND TOLERABILITY IN PARKINSON´S DISEASE

    A. Vinagre-Aragón, E. Mondragón-Rezola, I. Croitoru, A. Bergareche-Yarza, JJ. Poza-Aldea, A. Olaskoaga-Caballer, M. Iridoy-Zulet, M. Ruibal-Salgado, JC. Gómez-Esteban, K. Berganzo-Corrales, B. Tijero-Merino, J. Ruiz-Martínez (San Sebastián, Spain)

    Objective: to analyze the long term efficacy and tolerability of safinamide added as adjunctive therapy in a series of patients with Parkinson´s disease (PD) Background:…
  • 2019 International Congress

    Preclinical efficacy of drugs identified by IBM-Watson for repurposing to treat L-DOPA-induced dyskinesia

    N. Visanji, A. Lacoste, P. Ravenscroft, S. Spangler, S. Fox, A. Lang, J. Brotchie, T. Johnston (Toronto, ON, Canada)

    Objective: To test the efficacy of 3 drugs predicted by IBM Watson for Drug Discovery (WDD) as having the potential to treat L-DOPA-induced dyskinesia (LID).…
  • 2019 International Congress

    Exploring anti-hypertensives as possible disease modifying agents in Parkinson’s disease using artificial intelligence and epidemiology

    N. Visanji, S. Hensley Alford, A. Lacoste, P. Madan, I. Buleje, Y. Han, S. Spangler, L. Kalia, C. Marras (Toronto, ON, Canada)

    Objective: To apply machine learning and epidemiology to identify existing drugs that may have a disease modifying effect in Parkinson’s disease (PD). Background: Drug repurposing…
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