Corneal confocal microscopy: An imaging biomarker of neurodegeneration in Parkinson’s disease
Objective: The aim of the study is to investigate whether corneal confocal microscopy (CCM) can be used as a rapid, reliable, automated and non-invasive method…Case-control study of risk developing parkinsonism in Alzheimer’s disease in relation to hypertension, dyslipidemia, and diabetes in Taiwan
Objective: To clarify the relationship between vascular risk factors and parkinsonism in Alzheimer’s disease Background: This case-control study investigated the associations of a history of…Inhibitory Repetitive Transcranial Magnetic Stimulation of Pre-Supplementary Motor Area Improves Levodopa-Induced Dyskinesia in Parkinson’s Disease
Objective: To prove the causal role of pre-supplementary motor area (preSMA) in levodopa-induced dyskinesia using an interventional brain stimulation approach that targets abnormal preSMA activity. Background:…Correlation Between PDQ-39 and MDS-UPDRS Scores in a Phase 3 Randomized Controlled Trial of Patients with Parkinson’s Disease
Objective: To describe correlations of the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) part III scores with the 39-item Parkinson’s disease (PD) questionnaire…High-throughput screening using a Drosophila model of Parkinson’s disease
Objective: To identify potential therapeutic compounds for Parkinson’s disease (PD) treatment by combining a phenotype-based high-throughput screening assay in PD model flies with a validation…Increased vesicular monoamine transporter alleviate MPTP-induced impairment of neurogenesis
Objective: In this study, we employed vesicular monoamine transporter 2–overexpressing mice (VMAT2-HI) to investigate the influence of increased vesicular storage of catacholamines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced…Fall History and Gait Variability can Predict Falls in Individuals With Parkinson’s Disease
Objective: To understand the risk factors for falls in PD patients; To explore clinical indicators and Mobility Lab parameters that can predict falls in patients…Investigating Physical and Cognitive Changes over Two Years in Patients with Moderate to Late Stage Parkinson’s Disease in Northumbria
Objective: Investigate changes in timed up and go (TUG), grip strength, MoCA and MMSE scores and explore which areas of cognition are most commonly affected.…Influence of peripheral immune system on cognitive profile in Parkinson’s disease
Objective: To investigate the influence of the peripheral immune profile in the development of cognitive impairment in PD. Background: Dementia is frequent in advanced Parkinson’s…The effects of obstacle size and timing on prefrontal cortex activation in patients with Parkinson’s disease
Objective: To evaluate the effects of obstacle height and anticipation time on prefrontal cortex (PFC) activation in patients with Parkinson's disease (PD) and older adults.…
