Longitudinal progression of spatiotemporal parameters of turning in idiopathic Parkinson’s disease patients with Freezing of Gait
Objective: To develop predictive algorithms for freezing of gait (FOG) in Parkinson’s disease (PD) using longitudinal objective assessment of turning behaviors. Background: Freezing of Gait…Cerebellar rTMS theta burst for postural instability in progressive supranuclear palsy: a double blind cross-over sham controlled study using wearing sensors technology
Objective: To test the efficacy of a single theta burst cerebellar stimulation on postural instability in progressive supranuclear palsy using a cross-over design and wearing…Cortical FDG-PET patterns predict long-term motor progression and disability milestones in Parkinson’s disease
Objective: To evaluate the accuracy of single-subject FDG-PET in predicting motor and cognitive long-term progression in Parkinson's disease Background: The progression of Parkinson's disease is…Neuroinflammation and activation of Zif-268 in dyskinetic 6-OHDA-lesioned rats is counteracted by association of a 5-HT1A/1B receptor agonist and an A2A receptor antagonist
Objective: To evaluate whether an early treatment with the serotonin 5-HT1A/1B receptor agonist eltoprazine and the adenosine A2A receptor antagonist preladenant prevent the onset of…The Progressive Supranuclear Palsy Functional Disability Scale: Sensitivity to change
Objective: To determine the sensitivity to change within 12 months as well as completion time of the Progressive Supranuclear Palsy Functional Disability Scale (PSPFDS). Background:…Impulse control disorders and (romantic) jealousy in Parkinson’s disease: a patients’ vs. partners’ perspective
Objective: To compare self-reported symptoms of (romantic) jealousy and impulse control disorders (ICD) in Parkinson’s disease (PD) patients to those reported by their partners. Background:…Levodopa-carbidopa intestinal gel infusion: a video analysis of long-term effect on gait and posture
Objective: To investigate the long-term effect of levodopa-carbidopa intestinal gel (LCIG) on gait and posture by means of both clinical and objective measures in Parkinson’s…Association of Charcot-Marie-Tooth disease, Parkinson’s disease and FIG4 mutations
Objective: Here we report a patient with Charcot-Marie-Tooth (CMT) 4J disease (related to FIG4 mutations) who developed an early-onset Parkinson’s disease during evolution. Background: FIG4 encodes…Dyskinesia Rates in Patients with Parkinson’s Disease on CVT-301 (levodopa inhalation powder)
Objective: Analysis of dyskinesia as reported by PD diary, adverse events, UPDRS part IV dyskinesia score and examiner rated observation, during a phase 3 study…Aberrant structural connectivity of the executive network in Progressive Supranuclear Palsy
Objective: To ascertain the structural connectivity of the executive network in progressive supranuclear palsy (PSP) using probabilistic tractography. Background: Cognitive deficits are highly prevalent in…
