Serotonergic function in De Novo Parkinson’s Disease
Objective: We aimed to investigate the central serotonergic function in de novo PD and change in serotonergic function with dopaminergic medications. Background: While dopaminergic dysfunction…Shuffling gait may be pitfall in neurological examination in Parkinson’s disease
Objective: The purpose of this study is to investigate the gait in early stage of PD who did not complain of gait disturbance using three-dimensional…Central cholinergic activity and risk of falls in patients with Parkinson’s disease and freezing of gait
Objective: We evaluated whether changes in cholinergic function might be related to increased fall risk in PD patients with Freezing of Gait (FoG). Background: FoG…Ginsenoside Rb1 Prevents MPTP-Induced Changes in Hippocampal Memory via Regulation of the α-Synuclein/PSD-95 Pathway
Objective: To explore the effects of ginsenoside Rb1 on the cognitive impairment of Parkinson’s disease (PD) model. Background: Memory deficiency is a common non-motor symptom…Exploring the cognitive workload during a visual search task in Parkinson’s disease
Objective: To investigate cognitive workload during a visual search task in patients with Parkinson's Disease (PD) Background: Visual search is one of the most important…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…QPS over the supplementary motor area induced cortical excitability changes in human primary motor cortex: Comparison with Placebo effect
Objective: To explore the effects of quadripulse stimulation (QPS) over the supplementary motor area (SMA) in the healthy humans. Background: Repetitive transcranial magnetic stimulation (rTMS)…Motor learning and long duration response to levodopa in Parkinson’s disease.
Objective: To define the role of long-duration response (LDR) in motor learning, evaluating neurophysiological parameters in patients affected by Parkinson’s disease (PD) with and without…Unilateral increase of blink reflex recovery cycle in drug-naive hemiparkinson syndrome.
Objective: We assessed R2 Blink Reflex Recovery Cycle (R2 BRRC) in drug-naive Parkinson’s disease (PD) patients with unilateral tremor and/or rigidity, diagnosed as hemiparkinson syndrome,…Spatial distribution of functional clusters coding for reward and movement information in the striatal direct and indirect pathways
Objective: To obtain the insight how striatum processes reward based learning and motor information, we explored the responses of D1 and D2 medium spiny neurons…
