A review of modifiers of Parkinsonism in the Leucine-rich repeat kinase 2 (LRRK2) population
Objective: To review and examine the most current identified modifiers of Parkinsonism in the LRRK2 population. Background: LRRK2 is a protein with multiple domains and…Lack of TMEM230 mutations in patients with familial and sporadic Parkinson’s disease in a Taiwanese population
Objective: To confirm the role of mutations in transmembrane protein 230 (TMEM230) in a large number of PD patients and controls in a Taiwanese population.…Clinical evaluation of genetic changes of polymerase chain reaction in patients with PD at early stage
Objective: To assess the clinical feature of genetic changes in PARK1 (α-synuclein) and PARK2 with the help of PCR in patients with Parkinson’s disease and…Downregulation of blood serum microRNA 29 family in patients with Parkinson’s disease
Objective: The aims of the present study were to profile the expression of microRNA29 family (miR-29s) in blood serum from patients with PD vs unaffected…Polymorphisms of glutamatergic system genes are associated with levodopa-induced dyskinesia in Parkinson’s disease
Objective: We aimed to study the association between glutamatergic system gene polymorphisms (SLC1A2 – gene, coding excitatory acids transporter, and GRIN2A gene, coding a subunit…Tef polymorphism predicts the decline of sleep disturbances in Parkinson’s disease
Objective: Circadian dysfunction may contribute to the etiology of motor and non-motor symptoms of Parkinson’s disease (PD). The influence of polymorphisms of Cry1 rs2287161, Cry2…BDNF(V66M), EIF4G1(R1205H), VPS35(D620N) gene polymorphisms in South Indian PD Patients
Objective: To investigate the association of BDNF(V66M), EIF4G1(R1205H) and VPS35(D620N) polymorphisms in South Indian PD patients. Background: Parkinson’s disease (PD) is the most common form…Full sequencing and haplotype analysis reveals LRRK2 protective haplotype in REM sleep behavior disorder
Objective: To examine the role of LRRK2 mutations and variants in susceptibility for RBD. Background: Rapid eye movement (REM)-sleep behavior disorder (RBD) is, in most…Lysosphingolipids accumulation in macrophage model of Gaucher disease
Objective: The aim of this study was to investigate if GCase deficiency in macrophage model of GD lead to lysosphingolipids accumulation. Background: Mutations in the…Association analysis of miRNA-linked variants with Parkinson’s disease and multiple system atrophy in a large Chinese population
Objective: To explore the relationship between two miRNA-linked variants (SPPLB rs1128402 and PDXK rs2070535) and two neurodegenerative diseases (PD and MSA) in a large Chinese…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.