Impact of Late-onset REM Sleep Behavior Disorder on the Symptoms of Parkinson’s Disease
Objective: To investigate whether PSG-proven late-onset RBD is associated with the PD symptoms in the Japanese population. Background: Rapid eye movement sleep behavior disorder (RBD)…Gastrointestinal Symptoms and Enteric Nerve Dysfunction in A53T Mice
Objective: To investigate the relationship between α synucleinopathy-induced enteric neuropathy and gastrointestinal dysfunction in A53T mice. Background: Approximately 80-90% of PD patients suffer from GI…Off-painfull state in Parkinson’s disease patients: A redflag of complulsive behavior. Data from a PET-FDG study
Objective: The aim of this study was to investigate the neural underpinnings of the dopaminergic dysregulation syndrome( DDS ) during the “off-phase”. Background: The DDS…Validation of the French version of the Munich Dysphagia Test-Parkinson’s disease (MDT-PD) in a multilingual population of the Luxembourg Parkinson’s Study (HELP-PD)
Objective: To provide the psychometric validation of the French MDT-PD in the Luxembourgish multilingual population. Background: The MDT-PD, developed and validated in German [1], is…Is Heart Rate variability a differential biomarker in REM sleep behavior disorder, Parkinson’s disease, multiple system atrophy and progressive supranuclear palsy?
Objective: Heart rate deceleration capacity (DC) and heart rate variability index (HRVI) as potential biomarkers for autonomic dysregulation were studied in subjects (each group N=10)…Weight loss is associated with rapid striatal dopaminergic degeneration in Parkinson’s disease
Objective: To investigate whether weight loss has a longitudinal association with striatal dopaminergic degeneration in Parkinson's disease (PD). Background: Weight loss in PD is associated…Investigation of the incidences of non-motor symptoms in first-degree relatives and the spouses of patients with Parkinson’s disease
Objective: The first-degree relatives of PD patients (such as siblings) and the spouses living together for many years do not have classic motor symptoms. However,…Blockade D1-like and D2-like dopamine receptors within nucleus accumbens attenuate hyperalgesia responses in a 6-OHDA induced parkinson’s disease rat model
Objective: To investigate the role of blockade D1-like and D2-like dopamine receptors within nucleus accumbens attenuate hyperalgesia responses in a 6-OHDA induced parkinson’s disease rat…Motor and non-motor symptoms of a 7.5-year prospective study of patients with Parkinson’s disease
Objective: Previously, we retrospectively reported the prevalence and risks of motor and non-motor symptoms of a large number of patients (1453) with Parkinson’s disease (PD)…Validation of the Hong Kong Chinese version of NMSQuest (HK-NMSQ)
Objective: This study aimed to translate and validate a standard Hong Kong Chinese version of the NMSQuest (HK-NMSQuest) to assist in identification of NMS in…
