[11C]PK11195 PET Imaging Reveals Neuroinflammation in Dementia with Lewy Bodies: NIMROD Study
Objective: To determine if subjects with dementia with Lewy bodies(DLB) have increased microglial activation in vivo compared to matched healthy controls as assessed using PET…Impaired Color Vision in Patients with DLB or Prodromal DLB.
Objective: We sought to characterize the prevalence of color vision impairment in DLB patients and investigate how color vision impairment in DLB patients was associated with other…Neuropsychological profile of corticobasal degeneration, progressive supranuclear palsy and frontotemporal dementia patients
Objective: To study and compare the neuropsychological profile of patients with corticobasal degeneration (CBD), progressive supranuclear palsy (PSP), non-fluent progressive aphasia (NFPA) and frontotemporal behavioral…Cognitive and demographic predictors of progression to MCI and dementia in Parkinson’s disease
Objective: To determine the association between demographic and cognitive features and subsequent progression of cognitive symptoms in Parkinson’s disease (PD). Background: Most patients diagnosed with…Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
Objective: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments.…Association of arterial stiffness with cognition in patients with Lewy body disorder
Objective: We aimed to investigate the association between arterial stiffness and cognitive function in patients with Lewy body disorder (LBD), including Parkinson disease (PD) and…White matter lesions and peripheral vessel reactivity in dementia with Lewy bodies
Objective: We aimed to assess the significance of white matter hyperintensities (WMHs) in dementia with Lewy bodies (DLB) and their contribution to phenotype of the…Lack of accurate self-appraisal is equally likely in Mild Cognitive Impairment from Parkinson’s disease and Other Neurodegenerative Disorders
Objective: To determine whether Parkinson's disease patients with mild cognitive impairment (PD-MCI) demonstrate more accurate self-appraisals of their cognitive deficits than non-PD individuals with amnestic…Cholinergic activity, mobility, and attention in mild cognitive impairment
Objective: The aim of this investigation is to relate cholinergic activity (CA) to objective measures of balance, gait, and attention in a MCI and control…Adding cues to a rat gambling task potentiates the increase in premature responding in response to chronic D2/3 agonist ropinirole without mitigating preference for risk
Objective: Investigating the effect of chronic administration of the dopamine D2/3 agonist ropinirole on a cued model of gambling behaviour in rats. Background: Dopamine D2/3 agonists…
