Chronic levodopa treatment accelerates the disorders of circadian rhythm in 6-OHDA induced Parkinson’s disease model
Objective: We aimed to study the effect of levodopa on circadian rhythms in 6-OHDA lesioned rats, and to clarify whether the disturbance of the circadian…Influence of motor manifestation and onset’s side on the spectrum of non-motor symptoms in patients with Parkinson’s disease
Objective: To analyze Parkinson's disease (PD) motor manifestation and onset's side influence on the spectrum of non-motor symptoms (NMS). Background: Possibly the onset's side and…Unusual motor and non-motor symptoms and signs in the early stage of Parkinson´s disease
Objective: To present unusual motor and non-motor symptoms and signs in the early stage of Parkinson´s disease. Background: Patients with Parkinson´s disease (PD) may present…The combined effect of REM sleep behavior disorder and hyposmia on cognition and motor phenotype in Parkinson’s disease
Objective: We investigated the relationship between olfactory impairment, REM sleep behavior disorders (RBD), initial cognitive performance and motor phenotype in Parkinson's disease (PD). Background: Olfactory…Hypothalamic volume loss is associated with reduced melatonin output in Parkinson’s disease
Objective: Our aim was to compare hypothalamic volumes in PD patients with matched controls, and determine whether volume loss correlated with reduced melatonin output in…Premotor symptoms as prognostic indicators of Parkinson’s disease: A nationwide population-based and case-control study
Objective: To evaluate the association between the premotor symptoms and the prognosis of Parkinson's disease (PD) by utilizing Taiwan National Health Insurance Research Database. Background:…Pulmonary dysfunction in Parkinson’s disease: A feature of early disease?
Objective: To characterize the abnormalities in pulmonary function tests (PFT) in early-diagnosed PD patients and to assess their prognostic features 2 years after. Background: Pulmonary…Could smell test differ from scans without evidence of dopaminergic deficit and Parkinson’s disease?
Objective: To investigate the differences and similarities between SWEDD patients and PD patients using smell test. Background: The concept of SWEDD(scans without evidence of dopaminergic…Depression and anxiety in Parkinson’s disease with rapid eye movement sleep behavior disorder
Objective: To investigate whether rapid eye movement sleep behavior disorder (RBD) is associated with depression or anxiety in patients with Parkinson's disease (PD). Background: RBD…The heterogeneity of fatigue in different stages of Parkinson’s disease
Objective: To identify factors associated with fatigue in different stages of PD. Background: Fatigue is an important contributor to poor quality of life. However, it…
