Sympathetic Nervous System Overactivity in the Pre-Motor Stage of Parkinson’s Disease: Therapeutic Implications
Objective: To investigate sympathetic nervous system (SNS) activity in idiopathic REM behavior disorder (iRBD) subjects at risk for Parkinson's disease (PD), and the effect of…eHealth Technologies for People with Parkinson’s: Acceptance & Implications
Objective: To investigate the impact of eHealth on Parkinson's care, focusing on technology acceptance and examining ethical, legal, social, and medical aspects of wearables. Background:…Predictors of Death within 6 Months in Individuals with Dementia with Lewy Bodies
Objective: To assess predictors of death in the subsequent 6 months in dementia with Lewy bodies (DLB). Background: Individuals with DLB commonly die of disease-related…ORION: A Global Phase 3, Randomized, Double-Blind, Placebo-Controlled Trial of AMX0035 in Progressive Supranuclear Palsy (A35-009)
Objective: Here we describe ORION, a phase 3 trial assessing efficacy and safety of AMX0035 in progressive supranuclear palsy (PSP). Background: PSP is a rare,…Noradrenaline treatment of apathy and impulsivity in participants with Progressive Supranuclear Palsy syndromes (NORAPS). A Phase II clinical trial – ISRCTN99462035.
Objective: The NORAPS Phase II clinical trial seeks to demonstrate safety, tolerability and efficacy of atomoxetine in Progressive Supranuclear Palsy (PSP). Background: PSP is a…The Impact of Deep Brain Stimulation on the Embarrassment and Self-Esteem of Patients with Essential Tremor
Objective: To examine how Deep Brain Stimulation (DBS) influences embarrassment and self-esteem in patients with essential tremor (ET) and assess caregiver impressions. Background: Social embarrassment…PreActive-PD Telehealth Coaching to Increase Physical Activity in Early-Stage Parkinson Disease: A Randomized Controlled Feasibility Trial
Objective: To assess the feasibility/acceptability, and preliminary efficacy of Pre-Active PD intervention delivered via telehealth to increase physical activity (PA) engagement in people with early-stage…The Prospect of Exoskeletons for Individuals with Parkinson’s Disease: A Comprehensive Review
Objective: This comprehensive review provides a thorough analysis of the effects of robotic-assisted gait training on Parkinson's disease patients' gait parameters and makes recommendations for…A telehealth physical activity coaching program can maintain physical activity and exercise confidence in people with Parkison disease: a cohort study.
Objective: To examine the efficacy of the Engage-PD program in sustaining physical activity gains in people with Parkison disease. Background: Parkinson disease (PD) is a…Utility of Instrumented Timed Up and Go Test to Estimate Disease Severity in Huntington Disease.
Objective: To investigate the utility of Instrumented Timed Up and Go (TUG) test to estimate disease severity in people with Huntington Disease (PwHD). Background: Huntington…
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