The Impact of Bilateral STN- Deep Brain Stimulation on Motor Symptoms and Quality Of Life in Advanced Parkinson’s Disease: A Single Center’s Experience
Objective: The aim of this study was to examine the effects of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on motor symptoms and quality…Sex-Related Differences of Resting-State Brain Activity in Parkinson’s Disease
Objective: To investigate sex-related differences of resting-state functional magnetic resonance imaging (rs-fMRI) metrics in early-stage, untreated Parkinson’s disease (PD) patients. Background: Sex plays an important role in the heterogeneity of PD, but its effects…Rationale and Design of the Slowing Parkinson’s Early through Exercise Dosage – United Kingdom (Slow-SPEED-UK) Trial
Objective: Slow-SPEED-UK is a randomized controlled trial investigating the effects of an app-based exercise program on individuals at higher risk of Parkinson’s Disease (PD). Background:…Selecting an Imaging Biomarker for a Multi-Arm Multi-Stage Trial of Disease-Modifying Treatments for Parkinson’s: The EJS ACT-PD Experience
Objective: To report on the selection of an imaging biomarker for a sub-study in a multi-arm, multi-stage (MAMS) platform trial for disease-modifying therapies (DMTs) in…Holmes Tremor Treated with Pallidal Stimulation
Objective: To discuss the optimal target in deep brain stimulation (DBS) for Holmes tremor (HT) Background: Holmes tremor is a proximally dominant tremor with low…Remote recruitment of hyposmic participants identifies biomarkers related to neuronal alpha-synuclein disease
Objective: To evaluate the proportion of people with dopaminergic deficit and positive alpha-synuclein seed amplification assay (aSyn SAA) among a remotely identified group of hyposmic…Responsive morphometric fingerprints in deep brain stimulation for Parkinson’s disease
Objective: In this study, we identified differential network characteristics based on graph theory of structural covariance network (SCN) between responders and non-responders of DBS. Background:…Habenular Structural Connectivity Changes in Parkinson’s Disease: A 7T MRI Study
Objective: To assess if the structural connectivity of habenula (Hb) differs between Parkinson’s disease (PD) patients and healthy controls (HCs). Background: PD is marked by…Unraveling Plantar Pressure Dynamics in Parkinson’s Disease with Freezing of Gait: Taking Steps through Its Characters and Predictive Factors
Objective: To elucidate plantar pressure characteristics in different stages of PD patients who experienced FOG and identify predictive factors for alterations in plantar pressure parameters.…Long-Term Evolution of Advanced Parkinson’s Disease Burden: Subgroup Analysis from the 24 Month International PROSPECT Observational Study
Objective: To evaluate the long-term evolution of clinical outcomes and treatment patterns in people with advanced Parkinson’s disease (PwaPD) whose symptoms are inadequately controlled by…
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