A better understanding of Paediatric Paroxysmal Movement Disorders
Objective: To clinically characterise paroxysmal movement disorders (PxMD) and determine prevalence in a paediatric population for the first time. Background: Characterised by episodic involuntary movements,…Comparative analysis of opicapone and entacapone in the management of motor fluctuations in patients with Parkinson’s disease, from clinical trials to healthcare resource usage
Objective: To assess the differences between two catechol-O-methyltransferase (COMT) inhibitors, opicapone (OPC) and entacapone (ENT). Background: Opicapone and ENT are COMT inhibitors developed as adjunct…How Common is Essential Tremor in Germany? A Real-World Claims Data Analysis
Objective: To estimate the prevalence and incidence of essential tremor (ET) stratified by age and sex, using insurance claims data from a large representative [1,2]…Secondary orthostatic tremor associated with hyperthyroidism: A case report
Objective: To illustrate the electrophysiological and clinical findings in a patient with secondary orthostatic tremor (OT) associated with hyperthyroidism Background: Orthostatic tremor is a rare…Impact of Surrounding Audio-Visual Complexity on Symptomatology of Laryngeal Dystonia: A Virtual Reality Study
Objective: We examine the impact of surrounding audio-visual on Laryngeal Dystonia (LD) symptomatology to better understand its phenomenology. Background: LD is an isolated focal dystonia…Tractography-guided versus Clinical Determination of the Most Effective Contact for Tremor Control in Patients with Deep Brain Stimulation – A Clinical Trial
Objective: To prospectively test the hypothesis whether imaging-guided contact selection based on standardized individual tractography of the dentato-rubro-thalamic tract (DRTT) is non-inferior to clinical contact…Structural and Functional Brain Alterations in Laryngeal Dystonia: A Coordinate-Based Activation Likelihood Estimation Meta-Analysis
Objective: Efforts to understand laryngeal dystonia (LD) pathophysiology using neuroimaging techniques have demonstrated altered brain structure and function in patients compared to healthy controls1-5. However,…Expanding the concept of “occupational dystonia”: data from the Italian Dystonia Registry
Objective: This study aimed to investigate whether certain occupations are associated with an increased risk of developing specific focal forms of idiopathic adult-onset dystonia (IAOD),…Deep brain stimulation contact selection using Neurophysiology and Artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…Multicenter study of efficacy and safety of subcutaneous foslevodopa/foscarbidopa treatment initiation or switch from LD/CD intestinal gel
Objective: To describe a series of patients under treatment with subcutaneous foslevodopa/foscarbidopa, either as initiation therapy or after switching from intestinal levodopa/carbidopa. Background: Treatment with…
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