Clinical and Imaging Changes in Parkinson’s Disease Patients Under Spinal Cord Stimulation: A Double Blinded Analysis
Objective: Evaluate clinical and biomarker changes from spinal cord stimulation (SCS) in Parkinsons Disease (PD) under sham controlled randomized evaluation. Background: SCS has been proposed…Functional connectivity enhances prediction of STN DBS motor outcomes
Objective: To assess the predictive value of functional and volumetric MRI data in comparison to clinical data alone for STN DBS outcomes. Background: While STN…Levodopa response is an inadequate and often biased correlate of STN-DBS outcomes
Objective: To investigate the reliability of the relationship between levodopa response and subthalamic nucleus (STN) DBS outcomes in Parkinson disease (PD). Background: Levodopa response (LR)…Effect of Target Selection on Mood, Pain, and Medications after DBS in PD
Objective: To describe the association between medication adjustments with mood and pain following bilateral deep brain stimulation (DBS) in Parkinson’s disease (PD). Background: Depression, anxiety,…PD GENEration: A cross-sectional evaluation of cognitive complaints in Parkinson’s disease (PD) patients according to GBA1 and DBS status
Objective: To compare differences in cognitive complaints in Parkinson’s disease (PD) patients who are GBA1 mutation carriers and non-carriers either with or without DBS. Background:…Real-world Programming and Sensing from Adaptive Deep Brain Stimulation for Parkinson’s Disease in Japan
Objective: To characterize programming configurations and local field potentials (LFP) control parameters in a multicenter, real-world cohort of patients receiving deep brain stimulation (DBS) for…Parkinsonism after Internal Globus Pallidus Deep Brain Stimulation in Dystonia
Objective: To evaluate the frequency and predictors of parkinsonism after GPi-DBS in dystonia; to describe the clinical characteristics and stimulation changes performed to improve parkinsonism.…Cholinergic brain vulnerabilities associate with diabetic comorbidity in Parkinson disease
Objective: We aim to explore differences in brain cholinergic nerve terminal integrity between Parkinson's disease (PD) patients with and without comorbid diabetes, utilizing a highly…A novel single-cell reporter identifies regulators of the endogenous PINK1-Parkin mitochondrial quality control pathway
Objective: We aimed to identify genome-wide regulators of the PINK1-Parkin pathway using a novel flow cytometry reporter, endogenously tagged MFN2, as a readout of the…Opicapone as First-Line Strategy for the Treatment of Wearing-off in Korean Patients with Parkinson’s Disease
Objective: This study aimed to explore the efficacy of opicapone (OPC) 50 mg versus an extra 100 mg levodopa (L-dopa) dose to treat early wearing-off…
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