A Device Agnostic Pipeline for Gait Detection and Assessment in Free-living and Clinical Environments
Objective: To provide a framework for a device agnostic gait analytics pipeline for standardizing and improving quantitative gait analysis using wearable sensors. Background: Gait impairments…Artificial Intelligence Opportunities for Diagnostics of Dementia via Speech (Brainphone Project)
Objective: The aim of the clinical study was the assessment of efficiency of the screening diagnositics method for dementia by speech using AI-based technology (BRAINPHONE…Get Ready a mobile phone app a solution for patient engagement/remote management
Objective: The movement disorder DBS team at the Royal Victoria Infirmary, developed‘Get Ready®’ mobile phone app for patients who are candidates for DBS. The app…Creating myPPMI: an Online Portal to Deliver Study Participant Content
Objective: Building a centralized platform to collect patient reported outcomes and provide educational and informational content to participants Background: Patient portals are a valued healthcare…Examining and contextualizing free-living heart rate using multiple wearable sensors: a potential approach for assessing autonomic dysfunction in Parkinson’s disease?
Objective: To examine context-specific fluctuations in free-living heart rate (HR) across a week-long multi-sensor wear period in people with Parkinson’s disease (PD). Background: Non-motor symptoms,…Use of social media and health information technology among caregivers of Alzheimer’s disease and other neurological conditions: Secondary analysis of the 2022 Health Information National Trend (HINTS) Survey
Objective: This study aims to evaluate the pattern of health information seeking from social media and other health technology tools among caregivers for individuals with…Artificial Intelligence and Visual Analysis of Movements in Parkinson’s Disease
Objective: To evaluate the use of artificial intelligence in the analysis and classification of movements in Parkinson's disease. Background: Artificial intelligence (AI) is a powerful…Long-term effects of Deep Brain Stimulation on gait and postural control in Parkinson’s disease
Objective: To investigate the effects of deep brain stimulation (DBS) on gait and postural control in patients with Parkinson's disease (PD) two years after surgery.…Quantification of Neuroinflammation and White Matter Injury in Parkinson Disease Using Diffusion Basis Spectrum Imaging
Objective: To investigate differences in white matter (WM) using Diffusion Basis Spectrum Imaging (DBSI) between participants with Parkinson’s disease (PD) and controls and to examine…First-In-Human Single and Multiple Ascending Dose Trial Design of LY3962681, a Novel Intrathecally Delivered siRNA Targeting α-synuclein mRNA for the Treatment of Patients with Parkinson’s Disease
Objective: Development of a Phase 1 clinical trial evaluating LY3962681, a novel, intrathecally delivered siRNA directly targeting α-synucleinmRNA (SNCA) to reduce α-synuclein protein (ASYN), for the treatment of…
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