Selective subthalamic DBS improved non-motor disorders without affecting weight gain in parkinsonism
Objective: Evaluate the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on weight gain in Parkinsonian rats: The primary objective would be to determine whether…How Botulinum Toxin Transformed the American Food Industry
Objective: To highlight an episode of botulism that altered American food packaging technology Background: Early progress in understanding the behavior of botulinum toxin was marked…A Post-mortem Study on Striatal Glia and Blood Brain Barrier Integrity in Aging and PD Asian-Indians.
Objective: We examined the glial and blood brain barrier (BBB) changes related to normal aging and PD in the Asian-Indian striatum. Background: increases the risk…Boosting Parkinson’s Disease Diagnosis: How Training Ethiopian Healthcare Workers and Enhancing Community Level Awareness Led to a Surge in Case Identification
Objective: The study assessed the effectiveness of a capacity development training program in improving the diagnosis of Parkinson's Disease (PD) by healthcare professionals Background: Parkinson's…Engage, Educate and Empower: Parkinson’s Research Advocates from the Black and African American Community
Objective: To assess engagement in research advocacy among Black and African people with Parkinson’s and their care partners. Background: Black and African American people with…Alterations in Monoamine Metabolites in Parkinson’s Disease: A Meta-Analysis
Objective: To analyze the levels of various monoamine metabolites in patients with Parkinson’s Disease as compared to healthy controls. Background: Monoamine metabolites are the breakdown…Dynamic video-assessment of axial postural abnormalities in parkinsonism: feasibility and pilot analysis
Objective: To evaluate changes in the degree of axial postural abnormalities (APAs) using the AutoPosturePD software during standing and walking under single/dual-task conditions. Background: We…Can Heterozygous Autosomal Recessive Mutations Cause Neurological Disease?
Objective: To highlight the significance of heterozygous PLA2G6 and PRKN gene mutations in causing parkinsonism. Background: We report our observations in two families with multiple…Novel ASO Targeting IGHMBP2 Cryptic Splice Variant: Efficacy and Safety
Objective: Our objective was to target a specific cryptic splice site variant affecting immunoglobulin mu‐binding protein 2 (IGHMBP2) protein levels with a novel antisense oligonucleotide…A Rare Case of Parkinson’ s Disease Associated With Heterozygous ATP13A2 Gene Mutation: What If There Are No Atypical Features with a Later Onset?
Objective: Autosomal recessive mutations in ATP13A2 gene is a rare cause of levodopa-responsive parkinsonism with atypical features of supranuclear gaze palsy, spasticity, dystonia, dementia, myoclonus,…
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