Motor subtype stability and cognitive profiles in early Parkinson’s disease
Objective: To examine the association between motor subtypes’ stability and cognitive assessment scores across three years in early Parkinson’s disease (PD). Background: Past studies have…Exploring the effects of torsinA dysfunction in an iPSC-derived neuronal model of TOR1A dystonia
Objective: To investigate phenotypic differences between iPSC-differentiated cortical neurons derived from patients with TOR1A dystonia compared to healthy controls. Background: Primary generalised dystonia is most…Long-term follow up of Deep Brain Stimulation in Pantothenate Kinase-Associated Neurodegeneration Syndrome: two case reports
Objective: To present the long-term outcomes of deep brain stimulation in two cases of Pantothenate kinase-associated neurodegeneration (PKAN) syndrome. Background: PKAN syndrome is an autosomal-recessive…Longitudinal association of mild behavioral impairment with cognitive decline in Parkinson’s disease
Objective: To analyze the cross-sectional and longitudinal association between mild behavioral impairment and cognitive impairment in Parkinson’s disease. Background: Cognitive impairment and neuropsychiatric symptoms (NPS)…The effect of dopaminergic medication on force fluctuation in Parkinson’s disease
Objective: To quantify and compare muscle force variability during isometric dorsiflexion in male patients with Parkinson's Disease (PD), in the ON- versus OFF-medication state. Background:…Hearing impairment and non-motor symptoms in Parkinson’s disease: association and impact on quality of life
Objective: The aim of the study was to investigate the possible correlation between non-motor symptoms (NMS) burden and quality of life (QoL) with hearing impairment…Individual-specific brain functional connectivity mapping of therapeutic response in task-specific focal dystonia
Objective: Determine therapeutic effects of botulinum toxin on functional connectivity in individuals with task-specific dystonia. Background: Isolated task-specific dystonia occurs during specific activities, but not…Dystonia in the Middle East – The Cleveland Clinic Abu Dhabi Experience
Objective: This study aimed to evaluate the clinical spectrum of patients with dystonia seen at Cleveland Clinic Abu Dhabi Hospital (CCAD), a tertiary care center…Continuous subcutaneous foslevodopa/foscarbidopa: final results from a phase 3, open-label study
Objective: Evaluate safety and efficacy of foslevodopa/foscarbidopa (LDP/CDP) for patients with Parkinson’s disease (PD) in a 52-week, phase 3 study. Background: As PD progresses, patients…An in-vivo study of regional synaptic density loss in patients with Multiple System Atrophy using [11C]UCB-J PET molecular imaging.
Objective: We present preliminary, cross-sectional data, on the in-vivo evaluation of pre-synaptic terminal density in the brain of patients with Multiple System Atrophy (MSA) compared…
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