Dynamic functional connectivity changes and striatal dopamine deficiency in Parkinson’s disease
Objective: Using a multimodal neuroimaging approach, we assessed whether striatal dopamine synthesis capacity modulates the temporal dynamics of FC in PD. Background: The novel approach…Hereditary spastic paraplegia caused by mutations in SPAST, REEP1, or ATL1: A systematic review
Objective: The objective of our systematic review was to provide a review of hereditary spastic paraplegias (HSPs) regarding their genotype and clinical presentations. Background: Hereditary…Development of a Novel Questionnaire on Women’s Health to Understand Its Role in Parkinson’s Disease Development and Progression
Objective: Understand the role of women’s health and its effect on Parkinson’s disease (PD) and treatment outcome through a questionnaire available in English and Spanish.…Diagnosed and Drug-Treated Prevalence of Essential Tremor in Adult Patients: Retrospective Analyses of Two US Healthcare Claims Databases
Objective: Estimate the prevalence of diagnosed and drug-treated essential tremor (ET) in the adult population using 2 US healthcare claims databases. Background: ET is a…Apomorphine Sublingual Film Versus Subcutaneous Apomorphine in the Treatment of OFF Episodes in Parkinson’s Disease: Results From an Assessment of Patient Satisfaction
Objective: Evaluate treatment satisfaction with apomorphine sublingual film (SL-APO) vs subcutaneous apomorphine (SC-APO) for the treatment of OFF episodes in patients with Parkinson’s disease (PD).…Adults with slowly progressive dystonia-parkinsonism secondary to manganese accumulation
Objective: To expand the clinical spectrum of manganese-induced neurodegeneration. Background: Neurodegeneration induced by manganese accumulation is a potentially treatable condition and therefore should not be…Resting state functional brain networks associated with emotion processing in frontotemporal lobar degeneration
Objective: This study investigated the relationship between emotion processing and resting-state functional connectivity (rs-FC) of the brain networks in frontotemporal lobar degeneration (FTLD). Background: Defective…Novel bi-allelic variants in FBXO7 in a family with young-onset typical Parkinson’s disease
Objective: To describe the case of two brothers affected by typical young-onset Parkinson’s disease (PD), carrying novel compound heterozygous variants in FBXO7. Background: Bi-allelic mutations…DIFFERENCES IN KINEMATIC AND SPATIO-TEMPORAL PARAMETERS ASSESSED BY INSTRUMENTED “TIMED UP AND GO” TEST BETWEEN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS ASSOCIATED WITH PARKINSONISM AND PARKINSON’S DISEASE.
Objective: To assess differences in quantitative gait parameters and motility during standardized tasks between idiopathic Normal Pressure Hydrocephalus associated with Parkinsonism (iNPH-P) and Parkinson’s Disease…Symptomatic brain calcifications in two patients with JAM2 monoallelic variants.
Objective: To describe two subjects carrying monoallelic JAM2 genetic variant associated with brain calcification. Background: Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder…
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