Clinicopathologic features of primary lateral sclerosis with TDP-43 presenting as atypical parkinsonism
Objective: To clarify clinicopathologic features of pathologically-confirmed primary lateral sclerosis (PLS). Background: PLS is a neurodegenerative disorder characterized by slowly progressive upper motor neuron signs…Deep Brain Stimulation in Generalized Dystonia Caused by PRKRA Mutation
Objective: Dystonia is a hyperkinetic movement disorder with a complex pathophysiology. The medical treatment includes pharmacological treatment, including botulinum toxin (BoNT), which is considered the…Noninvasive focal delivery of Adeno Associated Vectors (AAV) with magnetic resonance-guided focused ultrasound in non-human primates
Objective: Focal brain delivery of gene therapy in non-human primates is a major step towards the translation of this technology for use in humans. We…Use of alternative healing for Parkinson’s disease in Kenya
Objective: To explore the experience of alternative healing practices by people with Parkinson’s disease in Kenya. Background: As a neurodegenerative condition, Parkinson’s disease (PD) requires…Systematic mapping of Parkinson’s disease gene interactions
Objective: Here, we aim to identify functional interactions between the Parkinson’s disease-associated genes. Background: Understanding how genes interact to produce a given phenotype is a…Understanding the continuing educational needs of US clinicians managing OFF episodes in Parkinson’s disease
Objective: This study sought to understand the continuing medical education (CME) needs of US-practicing neurologists (NEUROs) and neurology advanced practice providers (APPs) in managing patients with Parkinson’s Disease (PD) experiencing…Late-onset Treatment Resistant Isolated Oromandibular Dystonia: A case report
Objective: We hereby report a case of oromandibular dystonia with onset in late 70s and symptoms resistant to symptomatic therapy including onabotulinum toxin A. Background:…Antipsychotic use in Parkinson’s disease: a single center retrospective chart review
Objective: To assess the prevalence of antipsychotic (AP) use in people with Parkinson’s disease (PwP), and identify factors associated with AP prescription and differences in…Giant symptomatic capillary telangiectasia: uncommon cause of cerebellar ataxia
Objective: We present a case of a patient with adult-onset cerebellar ataxia and palatal tremor secondary to an uncommon vascular cause. Background: Capillary telangiectasias (CT)…Emotion Recognition in Multiple System Atrophy – an Eye-Tracking Study
Objective: To get better insights into emotion processing in patients with MSA-P compared to healthy controls (HCs) by using two different Eye-Tracking paradigms. Background: MSA…
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