Beneficial effects of cinnamaldehyde in orofacial dyskinesia in haloperidol-induced rat model
Objective: This investigation evaluates the effect of CA in orofacial dyskinesia in haloperidol-induced rat male model Background: Orofacial dyskinesias are involuntary repetitive movements of the…Expanding the armamentarium of clinical use of apomorphine in movement disorders.
Objective: To demonstrate the use of subcutaneous(SC) apomorphine injections in suspected untreated dopamine responsive conditions. Background: Apomorphine is a dopamine agonist historically used in dopamine…Exploratory analysis of the effect of delayed-start prasinezumab on motor sign progression measured with the Roche PD Mobile Application v2: PASADENA Phase II Parts 1 and 2
Objective: To determine whether the positive effects of prasinezumab on motor progression measured by Roche PD Mobile Application (PASADENA study Part 1; 0-52 weeks; NCT03100149)…Investigating inflammatory mechanisms in iPSC-derived LRRK2 microglia
Objective: To characterize microglial function and inflammatory mechanisms in LRRK2-associated Parkinson’s disease (PD). Background: PD is a neurodegenerative disease affecting primarily dopaminergic neurons of the…Network Fingerprint of Stimulation-Induced Speech Impairment in Parkinson’s Disease
Objective: To explore structural network correlates of stimulation-induced dysarthria (SID) in patients with Parkinson’s Disease (PD) chronically treated with deep brain stimulation (DBS) of the…Adult-onset axial dystonia: a rare condition that can lean on an early combined treatment approach
Objective: To describe a rare case of adult-onset axial dystonia treated successfully with a combined therapeutic approach. Background: Adult-onset truncal dystonia is an unusual condition…Movement disorders in pediatric anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis
Objective: Our aim was to investigate clinical characteristics and evolution of movement disorders (MD) in pediatric anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis. Background: Movement disorders account for…Myelination relevant plasma microRNA biomarkers identified via an innovative data analytic scheme for differential diagnosis of MSA, an Oligodendroglial Synucleinopathy
Objective: To establish an inclusive data analytic scheme to identify and characterize plasma microRNA biomarkers with pathophysiological significance for differentiating the atypical Parkinsonian, Multiple System…Feasibility of combining remote programming and remote monitoring towards a closed-loop DBS system
Objective: - Background: Deep Brain Stimulation (DBS) is an effective therapy for Parkinson’s Disease (PD). However, it is currently applied in an open-loop fashion and…Molecular alterations and pathological remodeling of colonic wall in patients with Parkinson’s disease
Objective: To evaluate, in an integrated manner, changes in faecal microbiota composition, morpho-functional alterations of the colonic mucosal barrier and changes of inflammatory markers in…
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