Meta-optimization to select stimulation settings for deep brain stimulation in Parkinson’s disease
Objective: The objective is to develop an algorithmic approach for selecting deep brain stimulation (DBS) settings for Parkinson’s disease (PD) and other movement disorders more…Clinically interpretable severity estimation of facial expression impairment in Parkinson’s disease
Objective: To develop a scalable and interpretable computer-vision based algorithm to measure the severity of facial impairment in Parkinson’s disease. Background: Neurological disorders frequently manifest…Clinical and Imaging features of Hyperkinetic Movement Disorders related with Stroke
Objective: To describe the characteristics of hyperkinetic movement disorders in patients with stroke. Background: Movement disorders (MD) related to cerebrovascular disease represent 22% of all…α-Synuclein molecular behavior and proteomic profiling distinguish subtypes of Lewy body disorders
Objective: We hypothesized that the clinical heterogeneity found in Lewy body disorders is a consequence of the molecular diversity of αSyn between different patients as…The effect of short-term treadmill exercise in the alpha-synuclein preformed fibril rat model of Parkinson’s disease
Objective: To determine how treadmill exercise impacts behavior and Parkinson-related pathology in the alpha-synuclein (a-syn) preformed fibril (PFF) model. Background: Exercise is often recommended by…Hidden effects of COVID-19 pandemic on Parkinson’s Disease: a telemedicine survey
Objective: The aim of this study was to report the telemedicine experience of our Movement Disorder Unit during COVID-19 pandemic and to assess the clinical…Quality of life changes after subthalamic stimulation for Parkinson’s disease depend on nonmotor and motor symptoms clusters
Objective: To analyze quality of life (QoL) changes after subthalamic stimulation (STN-DBS) based on a short list of baseline nonmotor and motor symptoms in Parkinson’s…The role of Parkinson Nurses for personalizing care in Parkinson’s Disease: a systematic review and meta-analysis
Objective: To identify the various roles and functions that Parkinson Nurses (PNs) may hold for personalized care of Patients with Parkinson’s (PwPs). Providing a systematic…Parkin deficiency impairs mtDNA dynamics and propagates inflammation
Objective: We sought to explore Parkin’s role in (i) averting neuronal mtDNA dyshomeostasis/release and (ii) the activation of downstream inflammatory processes. Background: Mutations in Parkin…Gene and variant curation of Parkinson’s disease genes by an authoritative expert panel
Objective: Establish an authoritative central curation for causative genes and variants for Parkinson’s disease (PD) Background: The urgency to establish central curation for causative genes…
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