TWNK in Parkinson’s disease: a Movement Disorder and Mitochondrial Disease Center perspective study
Objective: The aim of the study was to screen for TWNK variants in an Italian cohort of Parkinson’s disease (PD) patients, and to assess the…Prediction of early-stage Parkinson’s disease using connectivity and morphometry of the striatum
Objective: To parcellate the striatum into sub-regions and extract connectivity and surface morphometry features that can distinguish early patients with PD using machine learning. Background:…Phosphorylated α-synuclein at serine residue 129 decreased in Parkinson’s disease patients taking 250mg of daily niacin for six months
Objective: The main objective was to determine if α-synuclein could be modulated by niacin supplementation, contributing to improved Parkinson’s disease (PD) symptoms. Background: Niacin supplementation…Using fMRI-based multivariate pattern analysis to differentiate between hyperkinetic movement disorders
Objective: We aimed to investigate differences in functional magnetic resonance imaging (fMRI) brain responses across hyperkinetic movement disorders (HMDs) during a bilateral finger-tapping task.We aimed…Network detection and connectivity analysis to predict DBS-induced ataxia in essential tremor
Objective: We aim to differentiate networks associated with deep brain stimulation (DBS) induced ataxia in essential tremor (ET) patients and test if connectivity to these…Longitudinal study of clinical and neurophysiological features of essential tremor
Objective: This study investigates how motor and non-motor manifestations of essential tremor (ET) progress over time. Background: ET is a common and heterogeneous movement disorder…NODDI- based maps as potential marker for Parkinson’s Disease.
Objective: To assess the predictive power of Diffusion Kurtosis Imaging (DKI) parameters obtained from Neurite orientation dispersion and density imaging tool (NODDI) to differentiate between…Digital Biomarkers for Deep Brain Stimulation Programming in PD
Objective: This study investigates changes in EEG activity of Parkinson's disease (PD) patients with subthalamic nucleus (STN) deep brain stimulation (DBS) to identify neural biomarkers…Clove mediated Rescue in Parkinson’s Disease involves modulation of p53 and Sestrin2 in SHSY5Y cell line model
Objective: The study analyzed the neuroprotective effect of ethanolic extract of clove against Parkinson’s disease (PD) type toxicity in SHSY5Y cell line model and interrogation…Asymmetry of Motor and Non-motor Signs in Parkinson’s Disease: An Exploratory Clinical Case-control Study
Objective: To identify, quantify and correlate asymmetry between motor and non-motor signs in early Parkinson’s disease (PD). Background: Asymmetry of motor signs in PD reflects…
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