Does autosomal recessive Parkinson’s Disease behave as “Brain-first” subtype?
Objective: The aim of this study is to explore whether monogenic PD (due to parkin or DJ-1 homozygous mutations) can be subtyped as "brain-first" by…Heart rate variability is affected by standing and medication intake in Parkinson’s disease
Objective: To evaluate the effect of levodopa and orthostatism on heart rate variability (HRV) in a sample of consecutive subjects with Parkinson's disease (PD). Background:…Study of age related neurodegeneration of Cerebellum Basal Ganglia direct subcortical white matter tracts using fixel-based analysis.
Objective: The goal of the study is to use diffusion weighted imaging to confirm and expand on findings of structural tracks linking cerebellum (CB) and…Correlation between cognitive impairment and neuropsychiatric symptoms in Mexican persons living with Parkinson’s disease.
Objective: To describe the association amongst depression, anxiety, psychosis with cognitive impairment in Mexican people living with Parkinson’s disease (PwP). Background: Cognitive impairment and neuropsychiatric…Ocular ping pong movement to disentangle apathy from Bradykinesia in Parkinson’s disease
Objective: To disentangle bradykinesia from apathy through analysis of ocular movements. Background: While Parkinson's disease (PD) is mainly characterized by motor symptoms such as bradykinesia,…Optimization of a neuromelanin MRI protocol for use in a longitudinal study of substantia nigra depigmentation in early Parkinson’s Disease (the InsIght-PD study)
Objective: To optimize a neuromelanin-MRI (NM-MRI) protocol for robust and timely change analysis; and acquire serial NM-MRI data in controls and early Parkinson’s Disease (PD),…IgG to neurotensin in blood of Parkinson’s disease patients
Objective: The aim of the study was measurement of IgG to NT in blood plasma of Parkinson's disease patients. Background: Neurotensin (NT) is a 13-amino-acid…Critical Bilateral Carotid Disease presenting as Hemichorea
Objective: To present a case of combined contralateral internal carotid artery (ICA) occlusion and ipsilateral ICA critical stenosis presenting with isolated hemichorea. Background: Hemichorea consists…Axial hypotonia – A pointer towards NBIA – PLA2G6-Associated Neurodegeneration
Objective: While phenotypic spectrum of Neurodegeneration with brain iron accumulation is quite diverse, we discuss a case with peculiar axial hypotonia, a pointer towards PLA2G6…Motor and non-motor features of Parkinson’s disease in a large cohort of Gaucher’s disease patients
Objective: To investigate the prevalence of PD motor and non-motor clinical features and to characterize the prodromal phase of PD in a cohort of GD…
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