A Phase 2 Randomized, Double-blind, Placebo-controlled Trial of PRAX-944 for the Treatment of Essential Tremor
Objective: Evaluate the tolerability, safety and efficacy of PRAX-944, a selective small molecule T-type calcium channel blocker, for treatment of essential tremor (ET). Background: Essential…The profile of dysautonomia in the early stages of Parkinson’s disease and multiple system atrophy: the importance of using the SCOPA-AUT scale
Objective: To examine the profile of autonomic dysfunction and the utility of the SCOPA-AUT scale in distinguishing patients with early Parkinson's disease (PD) and MSA-parkinsonism (MSA-P)…Acute Stimulation-Induced Ataxia From Thalamic Deep Brain Stimulation
Objective: To characterize stimulation-induced ataxia in Essential Tremor patients treated with VIM DBS. Background: In Essential tremor (ET) patients with medically refractory tremor, deep brain…Automatic Speech Recognition for speech therapy in a Parkinson’s disease patient
Objective: The aim of the present study was to examine the Automatic Speech Recognition (ASR) technology as a useful approach to enhance the speech intelligibility…Feasibility Of An Intensive Inpatient Parkinson’s Rehabilitation Program For Moderately Advanced Parkinson’s Disease
Objective: To determine the feasibility in the US of a multimodal intensive inpatient Parkinson’s Rehabilitation program for patients with moderately advanced Parkinson’s disease (PD) Background:…A Mixed Methods Study on the Impact of Reading the Graphic Memoir My Degeneration: A Journey Through Parkinson’s on Patients with Parkinson’s Disease
Objective: To explore the impact of reading a graphic memoir on patients’ knowledge, mental health, and attitudes about living with Parkinson Disease (PD). Background: In…Verifying imaging accuracy for targeting and lead positioning in DBS: a phantom study.
Objective: In this phantom study we created an overview of the accuracy of four different modalities frequently used in DBS surgery and investigated the influence…Oro-bucco-lingual dyskinesia as a side effect of methotrexate therapy
Objective: to demonstrate association between the tardive dyskinesia and methotrexate therapy. Background: Dystonia is found among patients taking methotrexate. However, methotrexate and tardive oro-bucco-lingual dyskinesia…Cognition in Huntington’s Disease
Objective: Explore the cognitive profile of patients with Huntington’s Disease (HD) using a digital cognitive battery Background: Huntington’s Disease (HD) is a relentlessly progressive neurodegenerative…Early intervention with deep brain stimulation for children with ε-sarcoglycan myoclonus dystonia
Objective: To evaluate the efficacy and safety of Globus Pallidus Internus DBS (GPi-DBS) in early stages of disease course. Background: SGCE-related myoclonus-dystonia (SGCE-MD) is considered…
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