Gait ataxia and Autonomic dysfunction as early signs of Creutzfeldt-Jakob Disease: A Case Report
Objective: To highlight unusual early presenting symptoms of Sporadic Creutzfeldt-Jakob Disease (sCJD). Background: Prion diseases, a group of rare and fatal diseases caused by an…The clinical challenge of an unilateral abnormal uptake in datscan
Objective: Characterize patients with unilateral abnormal uptake in DaTscan. Background: Presynaptic dopamine transporter (DaT) single-photon emission computed tomography (SPECT) imaging is the most used imaging…Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson’s disease
Objective: Herein we evaluated the regional selectivity of presynaptic striatal dopaminergic denervation associated with RBD in drug-naive early PD. Background: REM sleep behavior disorder (RBD)…Pharmacological activation of Rev-erbα Provides Neuroprotection against Parkinson’s Disease
Objective: In this study, we investigated the effects of SR9009, a Rev-ERB agonist, on the dopaminergic system in the MPTP model of PD. Background: Circadian…Impact of SARS-CoV-2 vaccine in Parkinson’s disease
Objective: To evaluate the impact of SARS-CoV-2 vaccine on motor and non-motor symptoms in Mexican people with Parkinson's disease (PwP). Background: Nowadays, as a consequence…Brain structure alternations and disrupted functional connectivity in paroxysmal kinesigenic dyskinesia
Objective: This study aimed to delineate the morphological and functional alterations of paroxysmal kinesigenic dyskinesia (PKD) by functional magnetic resonance imaging (fMRI). Background: PKD is…Environmental exposures and clinical phenotype in a sample of patients with Parkinson’s disease in the southwestern Colombian region: preliminary results
Objective: Describe the clinical phenotype and environmental agents of patients from the Colombian southwestern region with familiar and sporadic Parkinson’s disease in a sample Background:…Factors that negatively impact the sexual function of men living with Parkinson’s disease
Objective: To investigate the impact of motor, non-motor function, and relationship quality on sexual function in men living with PD. Background: Among the non-motor alteration…LRRK2 Inhibition by BIIB122: Trial designs for two efficacy and safety studies in Parkinson’s disease patients with and without LRRK2 mutations (Lighthouse and Luma)
Objective: Describe Luma and Lighthouse, two studies that investigate efficacy and safety of BIIB122, a LRRK2 inhibitor. Background: Increased LRRK2 kinase activity has been linked…Role of surface EMG analysis in distinguishing clonic seizures from tremors
Objective: To compare surface EMG characteristics of clonic seizures with tremors. Background: Clonic seizures can clinically mimic tremors. In cases with poor or no EEG…
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