Re-thinking enrollment of Deep Brain Stimulation patients in Parkinson’s Disease Clinical Trials
Objective: To report on a survey of Parkinson’s disease (PD) experts on the inclusion of PD patients with deep brain stimulation (DBS) in clinical trials.…The Effects of Telepractice- Based LSVT-BIG Training in Patients with Parkinson’s Disease in Covid-19 pandemic: Preliminary Results
Objective: To investigate the effects of telepractice-based LSVT-BIG training on balance and mobility parameters in patients with Parkinson’s Disease (PD). Background: Patients with PD who…Measuring progression of Parkinson’s disease cardinal signs in the Phase 2 SPARK study
Objective: To evaluate a novel quantitative measure of Parkinson’s disease (PD) severity and progression in a Phase II clinical trial. Background: Cinpanemab, a monoclonal antibody,…Cinpanemab in Early Parkinson’s Disease: Phase 2 SPARK Study Results
Objective: To evaluate cinpanemab (BIIB054) efficacy and safety. Background: Aggregated alpha-synuclein (α-syn), a major constituent of Lewy bodies, is thought to play a central role…Climb up! Head up! Effectiveness and feasibility of sport climbing in Parkinson’s disease
Objective: The current study examines the effectiveness and feasibility of sport climbing in PD patients in a single-centre, randomised controlled, semi-blind trial. Background: Physical activity…Cuneiform Nucleus Deep Brain Stimulation for Freezing of Gait in Parkinson’s disease. Initial clinical report.
Objective: Here we report a first in human targeting of Cuneiform Nucleus (CnF) using MR tractography, observation of intraoperative stimulation patterns and stimulation precision benefits of…Amantadine DR/ER-Related Reduction in OFF and Dyskinesia Improved Patient-Rated Interference with Activities and Social Interactions
Objective: Evaluate dyskinesia and OFF interference with activities and experiences for persons with Parkinson disease (PWPD), and mitigation with treatment Background: OFF and Dyskinesia remain…Efficacy of a 6-week brisk walking program in improving non-motor symptoms in people with Parkinson disease – a randomized controlled trial
Objective: To examine whether the brisk walking program would be effective in alleviating non-motor symptoms, and improving sleep quality and health-related quality-of-life (HRQoL) in people…A new fully implantable Adaptive Deep Brain Stimulation system tested for the first time in patients with Parkinson’s Disease
Objective: This multicenter double-blind crossover study has been designed to evaluate the safety and efficacy of adaptive Deep Brain Stimulation delivered through an innovative IPG…Towards an automated rating of the MDS-UPDRS motor scores.
Objective: This study aimed at developing an automated rating method for the MDS-UPDRS motor scores in Parkinson’s disease (PD) patients. This automated rating uses inertial…
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