Evidence of gut dysbiosis in treatment-naïve de novo Parkinson’s disease
Objective: To determine the gut microbiome composition of treatment-naïve de novo Parkinson’s disease (PD) patients. Background: Over fifteen studies have independently demonstrated gut dysbiosis in…The Prodromal PD study – multiple biomarkers for early diagnosis?
Objective: The study aims to deepen our understanding of the prodromal phase of Parkinson’s disease (PD) Background: At the time of PD diagnosis, nigrostriatal degeneration…GBA Mutation Accumulates Higher Alpha-Synuclein in Alpha-Synucleinopathies
Objective: To investigate whether post-translational modifications of α-synuclein will give rise to species that differ between PD cases with N370S GBA mutation and WT-PD. Background:…HbA1c correlates with motor and cognitive outcome scores in patients with Parkinson’s disease and type 2 diabetes.
Objective: The objective of this study was to investigate the relationship between glycated haemoglobin (HbA1c) levels in blood and clinical outcomes (MDS-UPDRS III, MDS-UPDRS IV,…Gut, nasal and oral dysbiosis in Parkinson’s disease
Objective: We aimed to identify the nasal, oral, and gut microbiota dysbiosis associated with the presence and clinical manifestations of Parkinson’s disease (PD) using 16s…Evaluation of Acoustic Features of Speech for Monitoring Parkinson’s Disease Progression
Objective: Examine the temporal stability (i.e., repeatability) and sensitivity (i.e., change) of acoustic features of speech in people with Parkinson's Disease (PWP). Background: Voice and…Quantification of neck and trunk tilt during standing in Parkinson’s disease
Objective: We analyzed the motion of PD patients using the Markerless Motion Capture System (MLS) and examined the quantification of motion and its usefulness. Background:…Gut microbiota in patients with Parkinson’s disease (PD) predicts disease progression better than clinical features
Objective: To compare machine-learning models to predict the progression of PD using gut microbiota and clinical features. Background: A total of 21 studies including ours…Subclinical inflammation and Parkinson’s disease
Objective: To investigate subclinical inflammation in individuals with early drug-naive Parkinson’s disease (PD). Background: Neutrophil-to-lymphocyte ratio (NLR) is used as a marker of subclinical inflammation.…Daily fluctuations of plasma ghrelin level in patients with different motor subtypes of Parkinson`s disease
Objective: The objective of this study is to compare evening and morning plasma ghrelin level in patients with different motor subtypes of Parkinson`s disease (PD).…
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