Efficacy of Vitamin C for Restless Legs Syndrome: A Systematic Review and Meta‑analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy and safety of vitamin C (VITC) for treating restless legs syndrome (RLS) using evidence exclusively from randomized controlled trials (RCTs).…Rare Variant Analysis in Parkinson’s Disease Patients Stratified by Polygenic Risk
Objective: To identify rare variants that may contribute to Parkinson’s disease (PD) risk in individuals whose polygenic background does not adequately explain their disease status.…Efficacy and Adverse Events of Tetrabenazine, Deutetrabenazine, and Valbenazine in Huntington’s Disease
Objective: To compare the efficacy and safety of tetrabenazine, deutetrabenazine, and valbenazine for chorea and neuropsychiatric outcomes in Huntington’s disease (HD). Background: Vesicular monoamine transporter…GLP1R Expression and Parkinson’s Disease and Related Disorders in GLP-1RA–Treated Type 2 Diabetes
Objective: We tested whether interindividual differences in systemic GLP1R expression are associated with PDRD risk among adults with type 2 diabetes initiating GLP-1RAs. Background: Preclinical…Pregnancy and Breastfeeding in Early-Onset Parkinson’s Disease:Therapeutic Challenges of Levodopa Monotherapy.A case Report.
Objective: To describe the clinical course and treatment challenges of early-onset Parkinson’s disease (EOPD) during pregnancy and breastfeeding Background: Parkinson’s disease (PD) is rare in…Cervical Dystonia: The Objective Evaluation Of Muscle Tone
Objective: In this study, we aimed to assess the biomechanical components underlying the postural alterations characteristic of CD. In addition, we investigated the effects of…Nutrition and Dietary Assessment as a Wellness Factor in Parkinson’s Disease and Related Disorders
Objective: To characterize nutrition and food related concerns identified during supportive care visits for individuals with Parkinson’s disease (PD) and related disorders. Background: Individuals with…Association of Sarcopenia with Fear of Falling and Falls in patients with Parkinson’s disease
Objective: This study aimed to determine whether Sarcopenia is related to the risk of falls and to the Fear of Falling (FOF) in patients with…Underestimation of Nighttime Sleep Symptoms in Isolated RBD is Associated with Increased Risk of Phenoconversion to Synucleinopathy: A North American Prodromal Synucleinopathy Consortium Study
Objective: To determine whether mismatch between participant (PT) self-perceived and bed partner (BP)–reported sleep symptoms is associated with risk of phenoconversion to synucleinopathy. Background: Patients…Two Voices, One Disease: Patient and Care Partner Decision Dynamics on Advanced Therapies for Parkinson’s Disease
Objective: To characterize decision dynamics between patients with Parkinson’s disease (PwP) and their care partners (CP) on initiation of advanced therapies. Background: Factors guiding decisions…
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