Wearable Sensor-Driven Responsive Deep Brain Stimulation for Essential Tremor
Objective: To develop and clinically validate a responsive deep brain stimulation (R-DBS) paradigm – meaning stimulation would only be delivered when needed - driven by…Tremor in dystonia is associated with increased brain activity in the cerebellum and pallidum
Objective: To identify brain regions showing tremor-related activity in patients with dystonic tremor syndrome. Background: Dystonic tremor syndromes are highly burdensome and treatment is often…Somatosensory temporal discrimination in essential tremor treated with HIFU VIM thalamotomy: tremoric and lesional effects on the STDT
Objective: To compare somatosensory temporal discrimination threshold (STDT) with and without tremor in a cohort of essential tremor (ET) patients. Additionally, to compare STDT previously…The course of tremor in de novo PD: 7 year longitudinal analysis
Objective: To longitudinally describe the course and clinical characteristics of tremor in Parkinson Disease (PD) over a seven-year follow up. Background: Tremor is a cardinal…The sleep quality and its related factors of essential tremor patients
Objective: The objective of the study was to investigate the sleep quality and other sleep disorders among essential tremor (ET) patients and also to explore…Minimum detectable change of an automated algorithm derived spiral analysis parameter
Objective: To compute the minimum detectable change (MDC) of an automated algorithm derived spiral analysis parameter for quantification of upper limb action tremor.To compute the…Automated analysis of pen-on-paper spirals for tremor detection, quantification and differentiation
Objective: To develop and validate an automated analysis algorithm for pen-on-paper Archimedes spirals. Background: Spiral drawings are used in the clinic to identify and quantify…Dysautonomia and cognitive impairment in Essential Tremor: is there a link?
Objective: To investigate the relationship between autonomic dysfunction and cognitive impairment in Essential Tremor (ET). Background: Even though the term ‘essential’ was used to reflect…A phase 2b randomized, double-blind, placebo-controlled study of suvecaltamide in the treatment of adults with moderate to severe essential tremor: study design and methodology
Objective: Evaluate the efficacy and safety of JZP385 (formerly CX-8998), a highly selective T-type calcium channel modulator, for symptomatic control of moderate to severe essential…Validation of postural tremor model using regression and optimization
Objective: The purpose of this work is to validate a mathematical model of postural tremor to predict tremor at the hand from measurements of tremorogenic…
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