AMP PD: Collaborating in the discovery of biomarkers to accelerate the development of therapies for Parkinson’s disease
Objective: The Accelerating Medicines Partnership in Parkinson’s Disease (AMP PD; https://amp-pd.org) aims to identify and validate diagnostic, prognostic, and progression biomarkers for Parkinson’s Disease (PD).…Perampanel inhibits α-synuclein transmission in Parkinson’s disease models
Objective: To examine the effect of perampanel, an antiepileptic drug, on α-synuclein transmission in cultured cells and mouse models of Parkinson’s disease. Background: The intercellular transmission of pathogenic proteins…Central and Peripheral neurological manifestations of COVID-19 in a cohort of patients with Parkinson’s disease.
Objective: To describe central and peripheral neurological manifestations in patients with COVID-19 and Parkinson’s disease. Background: COVID-19 is associated with central and peripheral neurological manifestations.…Non-Tremor Motor Dysfunction is Associated with AD Biomarkers in Lewy Body Dementias
Objective: To investigate the clinical influence of Alzheimer’s disease (AD) co-pathology on motor features in Lewy Body Dementia (LBD). Background: There is considerable heterogeneity of…Arm swing instructions alter interlimb coordination but not prefrontal cortex activity of Parkinson’s disease persons.
Objective: This study compared the prefrontal cortex activity and interlimb coordination between PD persons and neurotypical individuals after receiving instructions to increase arm swing amplitude…Sleep disorders and future diagnosis of parkinsonism: a prospective study using the Canadian Longitudinal Study on Aging
Objective: To determine whether symptoms of insomnia, somnolence, apnea, and restless legs syndrome predict the diagnosis of parkinsonism after three years of follow-up. Background: Earlier…Associations between Baseline Cognitive Function and Gait Outcomes after Treadmill Training in Parkinson’s disease
Objective: To determine the effect of baseline cognition on gait outcomes after a gait training and aerobic exercise program in people with Parkinson's disease (PD).…Subjective cognitive complaints assessed with the cognitive domain of the Non-Motor Symptoms Scale predict longitudinal cognitive trajectory in people with Parkinson’s disease with normal cognition
Objective: To investigate whether subjective cognitive complaints assessed by the Non-Motor Symptoms Scale (NMSS) are predictive of longitudinal cognitive trajectories in cognitively intact people with…Informant vs. Self-ratings of Activities of Daily Living in Parkinson’s Disease patients
Objective: To compare patient and informant ratings of impairments in activities of daily living (ADL) of Parkinson’s Disease (PD) patients. Background: Valid ratings of ADL…Cognitive assessment of Parkinson’s Disease patients in a Northeast Brazilian population: Current Challenges
Objective: To evaluate the influence of education level in the Mini-Mental Status Examination (MMSE) score in Parkinson’s Disease (PD) patients in a northeast Brazilian sample.…
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