MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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  • 2018 International Congress

    Evidence for dysregulation of inflammatory mechanisms involving the NF-κB complex in the living parkinsonian brain

    S. Benoit, H. Xu, R. Alexandrova, G. Kaur, B. Thiruvahindrapuram, M. Hebb (London, ON, Canada)

    Objective: Sequence RNA in cortical samples taken from living PD patients to detect significant differentially expressed genes (DEGs) and altered biological pathways when compared to…
  • 2018 International Congress

    Clinical evaluation of genetic changes of polymerase chain reaction in patients with PD at early stage

    M. Salokhiddinov (Tashkent, Uzbekistan)

    Objective: To assess the clinical feature of genetic changes in PARK1 (α-synuclein) and PARK2 with the help of PCR in patients with Parkinson’s disease and…
  • 2018 International Congress

    Gender effects on clinical features in LRRK2 G2385R carriers and non-carriers in Parkinson’s disease

    S. Cui, S. Chen (Shanghai, People’s Republic of China)

    Objective: This study was to explore gender effects within the same genetic subtype and role of leucine-rich repeat kinase 2 (LRRK2) G2385R variants within the…
  • 2018 International Congress

    Parkinson-related CHCHD2 is necessary for oligomerization of ALS/FTD-related CHCHD10

    D. Narendra, X. Huang, B. Wu, Y. Liu, D. Nguyen, M. Marani (Bethesda, MD, USA)

    Objective: Characterization of isogenic CHCHD2, CHCHD10, and CHCHD2/10 double knockout out cell lines with assays of mitochondrial function, mitochondrial sublocalization, and homo- and heterodimerization. Background:…
  • 2018 International Congress

    Cerebellar atrophy in different motor and non-motor subtypes of Parkinson’s disease

    XX. Ma, CM. Li, W. Su, HB. Chen (Beijing, China)

    Objective: The cerebellum is involved in Parkinson’s disease (PD). This study was to investigate, using MRI and voxel-based morphometry (VBM), morphometric changes of cerebellum in…
  • 2018 International Congress

    Ultrasonographic signatures associated with movement disorders (USA-MD study): A population-based longitudinal study

    A. Crespo Cuevas, L. Ispierto, E. Lopez-Cancio, A. Planas, T. Canento, M. Hernandez-Pérez, R. Alvarez, D. Vilas (Badalona, Spain)

    Objective: To identify sonographic biomarkers of PD (Parkinson´s disease). Background: Study of Parkinson’s disease biomarkers could lead us to identify the disease at its earlier…
  • 2018 International Congress

    Research on nearinfrared brain function imaging for Freezing of Gait in Parkinson’s Disease

    Y. Jingjing, L. Zhanhua, C. Ming (Dalian, China)

    Objective: In the study ,fNIRS technique was used to study the activation level and activation mode of prefrontal cerebral cortex for patients with FOG under…
  • 2018 International Congress

    Microstructural changes in white and grey matter related to apathy, depression and anxiety in de novo Parkinson’s disease patients

    S. Prange, E. Metereau, A. Maillet, E. Lhommée, H. Klinger, P. Pelissier, D. Ibarrola, RA. Heckemann, E. Broussolle, A. Castrioto, L. Tremblay, V. Sgambato, P. Krack, S. Thobois (Bron, France)

    Objective: To study microstructural changes in grey and white matter in early drug-naïve Parkinson's disease (PD) patients and correlate these changes with neuropsychological manifestations. Background:…
  • 2018 International Congress

    Functional connectivity changes in relation to dopaminergic decline in Parkinson’s over time: A resting-state fMRI and 11C-PE2I PET imaging study

    W. Li, N. Lao-Kaim, A. Roussakis, A. Martín-Bastida, N. Valle-Guzman, G. Paul, E. Soreq, R. Daws, T. Foltynie, R. Barker, A. Hampshire, P. Piccini (London, United Kingdom)

    Objective: To evaluate the functional connectivity patterns of basal ganglia subdivisions in relation to dopamine transporter density and motor features in patients with PD at…
  • 2018 International Congress

    A longitudinal PET study to assess progression of laterality in Parkinson’s disease

    AA. Roussakis, N. Lao-Kaim, A. Martin-Bastida, P. Piccini (London, United Kingdom)

    Objective: This study aims to identify in Parkinson’s disease (PD) whether striatal dopamine transporter (DAT) losses occur at a similar rate in both sides of…
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