Huntington disease like 2 in South Africa
Objective: Background: Since the Huntingtin gene was identified in 1993, it has been recognized that a small proportion of patients with a clinical syndrome resembling…Evolution of Motor and Non-Motor Manifestations in Prodromal Parkinsonism
Objective: To trace the evolution of early motor and non-motor manifestations of synculeinopathy from the stage of idiopathic REM sleep behavior disorder (iRBD) until defined…Clinical profiles of late-onset psychiatric patients with incidental REM sleep without atonia
Objective: The clinical profiles of late-onset psychiatric patients exhibiting incidental REM sleep without atonia (RWA), which is a hallmark of REM sleep behavior disorder (RBD)…Effectiveness and costs of specialised physiotherapy given via ParkinsonNet: A retrospective analysis of medical claims data
Objective: To study the long-term benefits of specialised physiotherapy using the ParkinsonNet approach in real-world practice. Background: Trials show that specialised allied health interventions are…Antiglycine Receptor Antibodies and Rapidly Progressive Corticobasal Syndrome
Objective: To describe the first case of non-paraneoplastic autoimmune encephalitis with antiglycine receptor (anti-GlyR) antibodies manifesting as a Corticobasal Syndrome (CBS) and the response to…The Impact of short in-patient rehabilitation courses for people with Parkinson´s disease
Objective: To find out whether a 10 to 14 days group-based multidisciplinary in-patient rehabilitation course for patients with Parkinson´s disease has any long-term effect on…Clinical features and natural history of pathologically-confirmed corticobasal degeneration: A Japanese validation study of CBD (J-VAC study)
Objective: To elucidate the clinical features and natural history of CBD. Background: Recently, various clinical phenotypes of corticobasal degeneration (CBD) have been reported; on the…Probable MSA presenting initially with urinary retention
Objective: We describe 6 cases of probable MSA presenting with urinary retention/incomplete bladder emptying. Background: MSA is a progressive neurodegenerative adult-onset disease whose clinical features…PROMESA: A randomised, double-blind, placebo-controlled trial to evaluate the progression rate of MSA under EGCG supplementation as anti-aggregation-approach
Objective: To evaluate the safety and tolerability of epigallocatechin gallate (EGCG) in high doses and its efficacy to slow down disease progression in patients with…Referral and diagnostic time intervals from symptom onset to death in progressive supranuclear palsy (PSP), corticobasal degeneration (CBD) and Parkinson’s disease (PD)
Objective: To compare referral and diagnostic time intervals from index symptom to death in PSP/CBD and age-sex matched PD. Background: Misdiagnosis and delayed diagnosis are…
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