Fatigue and depression are predictors of the tremor form of Parkinson’s disease
Objective: The principal objective is to study the relationship between fatigue and depression with the peculiarities of the progress of PD. Background: Parkinson's disease (PD)…Dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder
Objective: This study is to investigate the correlations between the abnormalities in the distribution of striatal dopamine transporter (DAT) and the expression of Parkinson's disease…No association between Parkinson disease and autoantibodies against NMDA-type glutamate receptors
Objective: We measured NMDA antibodies in a large, well phenotyped sample of Parkinson patients without and with cognitive impairment (n = 297) and controls (n…No MPTP-induced behavioral deficits or Striatal field potential alterations in crossbreds of MPTP-susceptible and MPTP-resistant mice strains
Objective: To evaluate the electrophysiological and motor behavioural correlates of strain-dependent differential susceptibility of mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and the role of admixing thereon. Background:…Pupil evaluation as the test for the clinical manifestations of Parkinson’s disease
Objective: We clarify the correlation between abnormality in 123I-metaiodobenzylguanidine (MIBG) scintigraphy and task-evoked pupillary response in Parkinson's disease (PD) patients. Background: MIBG scintigraphy is one…Bone health and laboratorial correlations of Vitamin D in Parkinson’s disease
Objective: To evaluate the correlation between levels of 25 (OH)D (Vitamin D) and Bone Mineral Density (BMD) in a parkinsonian population. Background: Considering a limiting…Tau and α-synuclein autoantibodies as potential biomarkers for Parkinson’s and Alzheimer’s diseases
Objective: To investigate the value of the naturally occurring serum AIAs of α-synuclein (α-syn) and tau, proteins as potential biomarker for diagnosis of PD in…Partial depletion of peripheral M1 macrophages ameliorates the neuroinflammation and dopaminergic neuronal death in the brain of a MPTP-induced mouse model of PD
Objective: Neuroinflammation in the PD brain involves the activation of microglia and the increasing levels of inflammatory cytokines. Several studies have shown that the peripheral…Dietary habits, motor and cognitive impairment in Parkinson’s Disease
Objective: To evaluate the relationship between dietary habits, motor and cognitive impairment in Parkinson's disease patients with both cross-sectional and longitudinal design Background: Diet and…Examining Parkinson’s disease psychosis treatment outcomes in the real world: The insyte observational study
Objective: The INSYTE Study–seeks to gain a better understanding of the management of PDP. INSYTE will describe the relative safety and effectiveness of various antipsychotic…
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