Weight loss is associated with rapid striatal dopaminergic degeneration in Parkinson’s disease
Objective: To investigate whether weight loss has a longitudinal association with striatal dopaminergic degeneration in Parkinson's disease (PD). Background: Weight loss in PD is associated…No differences in the total burden of non-motor symptoms between Parkinson’s disease and non-degenerative parkinsonism
Objective: To compare the total burden of non-motor symptoms between Parkinson's disease and non-degenerative parkinsonism and to study the possible dopaminergic background of these symptoms.…Stigma and communication in people with Parkinson’s disease (PPD)
Objective: To present results about stigma in PPD from a Parkinson’s Workshop. These are preliminary results in the path to address the main project question…Freezing of gait recognition in Parkinson’s disease: A subject independent objective method
Objective: In this study, we aim to build an automated-FoG-detector for subject-independent. After extracting enormously relevant features, we apply variance detection-techniques to identify-FoG-events. Background: Gait…Profiles of microRNA in cerebrospinal fluid could be potential biomarkers for identifying motor subtype of Parkinson’s disease
Objective: We investigated CSF miRNA expression in PD and control subjects. We also evaluated if specific miRNA were differently expressed according to motor subtype of…Cell and animal models lacking RAB39B show biochemical and behavioural phenotypes that model aspects of Parkinson’s disease
Objective: To determine the pathogenic mechanisms underlying RAB39B-mediated Parkinson’s disease (PD). Background: PD is a neurodegenerative disorder characterized by loss of dopaminergic neurons in the…Determination of falling direction in Parkinson’s disease patients using a wearable sensor
Objective: The aim of this study is to objectively detect falls and their direction in Parkinson’s disease (PD) patients during everyday activities. Background: Falling is…Neuroprotection effects of probiotics strains on a chronic MPTP-induced mouse model of Parkinson’s disease
Objective: To explore the effects of probiotics strains on the neuroinflammation and degeneration of dopaminergic neurons in chronic Parkinson’s disease (PD) mice model. Background: Microglia-mediated…Speech intelligibility and comprehensibility in Slovak patients with Parkinson’s disease
Objective: The aim of our study was to evaluate intelligibility and comprehensibility (intelligibility in context) and its relationship with MDS-UPDRS (sub)scores in Slovak population of…α-synuclein antibody 5G4 identifies manifest and prodromal Parkinson’s disease in colonic mucosa
Objective: The aim of this study was to evaluate colonic mucosa staining using the 5G4 antibody, specific only for the disease-associated form of α-synuclein, in…
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