Partial depletion of peripheral M1 macrophages ameliorates the neuroinflammation and dopaminergic neuronal death in the brain of a MPTP-induced mouse model of PD
Objective: Neuroinflammation in the PD brain involves the activation of microglia and the increasing levels of inflammatory cytokines. Several studies have shown that the peripheral…Dietary habits, motor and cognitive impairment in Parkinson’s Disease
Objective: To evaluate the relationship between dietary habits, motor and cognitive impairment in Parkinson's disease patients with both cross-sectional and longitudinal design Background: Diet and…Examining Parkinson’s disease psychosis treatment outcomes in the real world: The insyte observational study
Objective: The INSYTE Study–seeks to gain a better understanding of the management of PDP. INSYTE will describe the relative safety and effectiveness of various antipsychotic…Validation of a One-Page Impulse Control Disorder Questionnaire in a Parkinson’s Disease Clinic
Objective: We seek to report data on ICD symptoms collected on 120 patients with Parkinsonism attending specialist movement disorder outpatient clinics using a newly devised,…The Inter-rater Reliability of Parkinson’s Disease Sleep Scale 2 Indonesian Version
Objective: The objective is to create reliable version of Parkinson’s Disease Sleep Scale 2 in Indonesian language. Background: Sleep disorder is one of the most…A German-Austrian multicenter, non-interventional, prospective study for the treatment with abobotulinumtoxinA injections in naïve and previously treated patients suffering from cervical dystonia
Objective: In this prospective, multicenter, non-interventional study (NCT01840462) the primary objective was effectiveness of abobotulinumtoxinA in BoNT treatment-naïve and previously treated subjects after two injection…Safinamide in Parkinson’s disease
Objective: To evaluate clinical effects, safety and tolerability of safinamide add-on levodopa in Parkinson’s disease (PD) patients. Background: Safinamide is a recently approved adjunctive treatment…Open-label extension (OLE) of a multiple ascending dose (MAD) study of BIIB092 in participants with PSP: Safety analysis
Objective: To assess safety of BIIB092 in participants with progressive supranuclear palsy (PSP) in an OLE of a MAD study. Background: BIIB092 is a humanized…Cognitive effects of SIRT6 overexpression: Emerging role of astrocytes
Objective: The aim of this work was to elucidate the effect of SIRT6 overexpression on cognition. Background: Recent evidence show that astrocytes are important for higher brain…Tardive Myoclonus: A Case Report
Objective: To report a patient with late-onset myoclonus after treatment with antipsychotic drugs which is a rare variant of tardive movement disorders. Background: The use…
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