Mov Disord Vol 33, Suppl 2 Archives - Page 167 of 177 - MDS Abstracts

2018 International Congress
Tremor in motor neuron disease may be central rather than peripheral in origin
A. Latorre, L. Rocchi, M. Stamelou, A. Batla, M. Ciocca, B. Balint, K. Sidle, A. Berardelli, J. Rothwell, K. Bhatia (London, United Kingdom)
Objective: To investigate the pathophysiology of action tremor in motor neuron disease (MND). Background: MND refers to a spectrum of degenerative diseases affecting motor neurons.…
2018 International Congress
Neuropsychological and clinical assessment for the differential diagnosis of patients with PDD vs. DLB
E. Fiorenzato, L. Weis, V. Camparini, F. Pistonesi, R. Schifano, E. Gasparoli, A. Antonini, R. Biundo (Venice, Italy)
Objective: To explore the role of clinical neuropsychological tools in Parkinson’s disease-dementia (PDD) vs. dementia with Lewy bodies (DLB). First, to define the feasibility of…
2018 International Congress
The Association Between Inhibitory Control and Freezing of Gait Severity in Parkinson’s Disease
E. Bayram, S. Banks, J. Longhurst, B. Bluett (Las Vegas, NV, USA)
Objective: To investigate the relationship between inhibitory control and freezing of gait (FOG) severity in Parkinson’s disease (PD). Background: Inhibition deficits play a role in…
2018 International Congress
Subcortical and Cortical 123I-FP-CIT binding deficits and mild cognitive impairment in Parkinson’s disease
A. Pilotto, F. Schiano DiCola, E. Premi, V. Garibotto, A. Scalvini, R. Turrone, R. Grasso, B. Bigni, S. Gipponi, B. Paghera, MC. Rizzetti, b. Borroni, A. Padovani (Brescia, Italy)
Objective: The objective of the study was to evaluate the relationship between basal ganglia and cortical 123I-FP-CIT binding and early cognitive deficits in PD. Background:…
2018 International Congress
Multi-limb dual-task cost in Parkinson disease: Evaluating effects of implicit and explicit cues
T. McIsaac, R. Cohen, R. Bay, J. Gupta, C. Adler (Mesa, AZ, USA)
Objective: To evaluate the effects of explicit and implicit task prioritization on reaching and foot-pedal tracking in people with Parkinson disease (PD). Background: PD affects…
2018 International Congress
α-Synuclein induced dopaminergic neurons mitochondrial dysfunction via cytochrome c oxidase subunit 2
D. Lin (Guangzhou, China)
Objective: To investigate the mechanism of how α-Syn injure the the dopaminergic neurons. Background: The misfolded α-Synuclein(α-Syn) transferring from cells to cells as prion protein…
2018 International Congress
Association of GALC, ZNF184 and rs2280104 with PD in southern Chinese
G. Li, J. Liu, S.S. Cui, J.J. Du, P.C. Zhang, J.F. Ma, S.D. Chen (Shanghai, China)
Objective: The aim of the study was to investigate the relationship between 12 single nucleotide polymorphisms (SNPs) and Parkinson’s disease (PD) in Chinese population. Background:…
2018 International Congress
Identification of gut microbial genes in Parkinson’s disease by shotgun metagenomic analysis
Y. Qian, X. Yang, S. Xu, S. Chen, Q. Xiao (Shanghai, China)
Objective: To carry out deep analysis on gut microbiome in patients with Parkinson’s disease (PD) and to evaluate the potential application for diagnosing PD patients…
2018 International Congress
Lysosphingolipids accumulation in macrophage model of Gaucher disease
M. Nikolaev, A. Kopytova, K. Senkevich, A. Emelyanov, G. Baydakova, E. Zakharova, G. Salogub, S. Pchelina (Gatchina, Russian Federation)
Objective: The aim of this study was to investigate if GCase deficiency in macrophage model of GD lead to lysosphingolipids accumulation. Background: Mutations in the…
2018 International Congress
The Parkinson’s Families Project: A family-based study of early onset and familial Parkinson’s disease
M. Tan, A. Costantini, S. Lubbe, E. Brown, J. Bras, N. Wood, A. Schapira, J. Hardy, H. Morris (London, United Kingdom)
Objective: The aim of this study is to identify new genetic variants that cause or predispose to Parkinson’s disease (PD). Our secondary aim is to…