Mov Disord Vol 33, Suppl 2 Archives - Page 72 of 177 - MDS Abstracts

2018 International Congress
Cognitive Impairment and Depression in Patients with Parkinson’s Disease
XD. Qu, SS. Li (Lanzhou, China)
Objective: To evaluate cognitive impairment and depression in patients with Parkinson's Disease (PD) and its relationship. Background: Patients with Parkinson's disease are prone to cognitive…
2018 International Congress
Distinct networks contribute to the dysexecutive and posterior cortical cognitive syndromes of cognitive impairment in Parkinson’s Disease
S. Lang, S. Jobert, B. Mejia-Constain, C. Degroot, A. Lafontaine, A. Hanganu, P. Bellec, O. Monchi (Calgary, AB, Canada)
Objective: The objective of the current study is to relate the network degeneration and the dual syndrome hypothesis of cognitive impairment in Parkinson’s Disease (PD).…
2018 International Congress
Integrated whole exome sequencing and chromosomal microarray in familial Parkinson’s disease
L. Robak, R. Du, B. Yuan, S. Gu, Z. Akdemir, J. Jankovic, J. Lupski, J. Shulman (Houston, TX, USA)
Objective: To determine whether whole exome sequencing (WES) plus chromosomal microarray analysis (CMA) yield a genetic etiology in a cohort of 110 individuals with familial…
2018 International Congress
Nucleotide repeats as genetic risk factors in a Swedish Parkinson’s disease cohort
J. Laffita Mesa, L. Brodin, P. Svenningsson (Stockholm, Sweden)
Objective: To search for abnormal NRE in the following genes: ATXN2, ATXN3, CACNA1A, TBP, c9orf72, PRNP, POLG1A and TOMM40 in a Swedish PD cohort. Background:…
2018 International Congress
Downregulation of blood serum microRNA 29 family in patients with Parkinson’s disease
YL. Tang, J. Wang (Shanghai, China)
Objective: The aims of the present study were to profile the expression of microRNA29 family (miR-29s) in blood serum from patients with PD vs unaffected…
2018 International Congress
Association of GBA polymorphisms and mutations with dementia in Parkinson disease: A 7-year study of three population-based incident cohorts
K. Lunde, J. Chung, I. Dalen, K. Pedersen, J. Linder, M. Domellöf, E. Elgh, A. Macleod, C. Tzoulis, J. Larsen, O. Tysnes, L. Forsgren, C. Counsell, G. Alves, J. Maple-Grødem (Stavanger, Norway)
Objective: To study the effect of GBA variants on dementia in three deeply phenotyped population-based prospective cohorts of patients with incident Parkinson disease. Background: Dementia…
2018 International Congress
Molecular mechanisms of GCH1-associated Parkinson’s disease
J. Terbeek, W. Vandenberghe (Leuven, Belgium)
Objective: To unravel the molecular mechanisms by which loss of GCH1 function enhances the risk of Parkinson´s disease (PD). Background: Loss-of-function mutations in GCH1 are…
2018 International Congress
Exploring novel diffusion-derived biomarkers in Parkinson’s disease Freezing of Gait
B. Bluett, E. Bayram, S. Banks, Z. Mari, K. Sreenivasan, X. Zhuang, Z. Yang, C. Bird, D. Cordes, I. Litvan, V. Mishra (Las Vegas, NV, USA)
Objective: To explore the association between novel diffusion-derived structural imaging biomarkers and disease duration in Parkinson’s disease with freezing of gait (PD-FOG). Background: Increasing free-water…
2018 International Congress
STN DBS modulates cortical auditory processing in advanced Parkinson’s Disease; a MEG-study
K. Valkonen, J. Mäkelä, K. Airaksinen, J. Nurminen, R. Kivisaari, E. Pekkonen (Helsinki, Finland)
Objective: To find out how deep brain stimulation (DBS) impacts cortical auditory processing in advanced Parkinson's disease (PD) patients. Background: Motor symptoms of PD can…
2018 International Congress
Putaminal dopamine depletion in de novo Parkinson’s disease predicts future development of wearing-off
S.J. Chung, Y. Lee, J.S. Oh, J.S. Kim, P.H. Lee, Y.H. Sohn (Goyang, Republic of Korea)
Objective: The present study aimed to investigate whether the level of presynaptic dopamine neuronal loss predicts future development of wearing-off in de novo Parkinson’s disease.…