Resting state networks abnormalities among healthy LRRK2 mutation carriers
Objective: To assess the integrity of resting state networks in non-manifesting carriers of the G2019S mutation in the LRRK2 gene. Background: Non-manifesting first degree relatives…Lack of TMEM230 mutations in patients with familial and sporadic Parkinson’s disease in a Taiwanese population
Objective: To confirm the role of mutations in transmembrane protein 230 (TMEM230) in a large number of PD patients and controls in a Taiwanese population.…MicroRNAs as Biomarkers for Parkinson’s Disease
Objective: To identify potential biomarkers for Parkinson’s disease by evaluating miRNA in cerebrospinal fluid samples collected from PD and healthy control subjects. Background: The diagnosis…Therapeutic Drug Monitoring and Pharmacogenetic Tests as Tools in Pharmacovigilance of Anti Parkinson’s Therapy
Objective: Parkinson's disease (PD) is the second most prevalent neurodegenerative disease worldwide, affecting more than 7 million people worldwide. However, treatment outcome in many patients…EEG microstates changes in response to increase in dopaminergic stimulation in treated typical Parkinson’s disease patients without clinical fluctuations
Objective: Neurotropic drugs may modulate Electroencephalography (EEG) microstates (MS), but there are no works showing EEG MS default-mode network changes in response to dopaminergic stimulation…Parkinson’s disease motor symptoms are linked to red nucleus volume and cerebellar metabolism
Objective: To investigate the involvement of the red nucleus (RN) and cerebellum in the motor symptoms of Parkinson's disease (PD). Background: Numerous studies have shown…Cognitive networks in Parkinson’s Disease Mild Cognitive Impairment: Salience Network disruption without gray matter loss
Objective: To identify neural correlates of mild cognitive impairment in Parkinson’s disease (PD-MCI) according to Level-I Movement Disorders Task Force Criteria (MDS-TF) (1), using a…Abnormal Functional Connectivity in Cerebellar Locomotor Region is associated with the severity of freezing of gait in patients with Parkinson’s disease
Objective: We aim to analyze cerebellar functional connectivity (FC) in PD patients with FOG (PD-FOG). Background: Freezing of gait (FOG) is a disabling disorder frequently…Three Tesla susceptibility-weighted MR imaging of parkinsonism and idiopathic REM sleep behavior disorder: Comparison with 123I-FP-CIT SPECT
Objective: The aim of this study was to assess the diagnostic performance of 3 Tesla susceptibility-weighted MRI (3T-SWI) and the concordance between the loss of…Resting state fMRI points to disparate brain network activations in early Parkinson’s disease
Objective: To perform an exhaustive comparison of brain networks identified through functional MRI (fMRI) in a small cohort of patients with idiopathic Parkinson’s disease (IPD)…
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